AIM: We studied the changing trend and factors associated with persistent diarrhoea (PD) in under-five children presenting to a large diarrhoeal disease hospital in urban Dhaka, Bangladesh, over the last two decades. METHODS: We used an unmatched case-control design, with a case (persistent diarrhoea; n=944) to control (acute diarrhoea; n=2832) ratio of 1:3 attending the Dhaka Hospital of icddr,b between 1991 and 2010. RESULTS: The proportion of children with PD decreased significantly from 8% in 1991 to 1% in 2010. The proportion of breastfeeding practices, measles vaccination coverage and vitamin A supplementation among 12-59 months old improved from 79% to 85%, 69% to 85% and 26% to 74%, respectively, which were significant. Although the isolation of rotavirus from stool in children with PD and acute diarrhoea increased, the isolation of Shigella spp., and Vibrio cholerae O1 decreased significantly. In a logistic regression analysis, wasting (OR=1.62), use of antibiotic before attending hospital (OR=5.94), absent clinical dehydration (OR=1.53) and bloody/mucoid stool (OR=3.33) were significantly associated with persistent diarrhoea. CONCLUSION: There, thus, is a need to integrate an appropriate and sustainable deterrent strategy to take the benefit of the significant reduction in prevalence as well as risks of PD in such population.
AIM: We studied the changing trend and factors associated with persistent diarrhoea (PD) in under-five children presenting to a large diarrhoeal disease hospital in urban Dhaka, Bangladesh, over the last two decades. METHODS: We used an unmatched case-control design, with a case (persistent diarrhoea; n=944) to control (acute diarrhoea; n=2832) ratio of 1:3 attending the Dhaka Hospital of icddr,b between 1991 and 2010. RESULTS: The proportion of children with PD decreased significantly from 8% in 1991 to 1% in 2010. The proportion of breastfeeding practices, measles vaccination coverage and vitamin A supplementation among 12-59 months old improved from 79% to 85%, 69% to 85% and 26% to 74%, respectively, which were significant. Although the isolation of rotavirus from stool in children with PD and acute diarrhoea increased, the isolation of Shigella spp., and Vibrio cholerae O1 decreased significantly. In a logistic regression analysis, wasting (OR=1.62), use of antibiotic before attending hospital (OR=5.94), absent clinical dehydration (OR=1.53) and bloody/mucoid stool (OR=3.33) were significantly associated with persistent diarrhoea. CONCLUSION: There, thus, is a need to integrate an appropriate and sustainable deterrent strategy to take the benefit of the significant reduction in prevalence as well as risks of PD in such population.
Authors: Katharine A Schilling; Richard Omore; Gordana Derado; Tracy Ayers; John B Ochieng; Tamer H Farag; Dilruba Nasrin; Sandra Panchalingam; James P Nataro; Karen L Kotloff; Myron M Levine; Joseph Oundo; Michelle B Parsons; Cheryl Bopp; Kayla Laserson; Christine E Stauber; Richard Rothenberg; Robert F Breiman; Ciara E O'Reilly; Eric D Mintz Journal: Am J Trop Med Hyg Date: 2017-07 Impact factor: 2.345
Authors: Michael A Efunshile; Bethrand A F Ngwu; Jørgen A L Kurtzhals; Sumrin Sahar; Brigitte König; Christen R Stensvold Journal: Am J Trop Med Hyg Date: 2015-06-22 Impact factor: 2.345
Authors: Sumon Kumar Das; Mohammod Jobayer Chisti; A M Shamsir Ahmed; Mohammad Abdul Malek; Shahnawaz Ahmed; K M Shahunja; Farzana Ferdous; Fahmida Dil Farzana; Jui Das; Aminur Rahman; Abdullah Al Mamun; Abu Syed Golam Faruque Journal: BMC Public Health Date: 2015-07-12 Impact factor: 3.295
Authors: Mohammad Habibur Rahman Sarker; Sumon Kumar Das; Shahnawaz Ahmed; Farzana Ferdous; Jui Das; Fahmida Dil Farzana; Abu S M S B Shahid; K M Shahunja; Mokibul Hassan Afrad; Mohammad Abdul Malek; Mohammod Jobayer Chisti; Pradip Kumar Bardhan; Md Iqbal Hossain; Abdullah Al Mamun; Abu S G Faruque Journal: PLoS One Date: 2014-08-29 Impact factor: 3.240