Literature DB >> 227327

Cytogenesis in the rat adrenal cortex: evidence for an ACTH-induced centripetal cell migration from the zona glomerulosa.

A S Belloni, G Mazzocchi, V Meneghelli, G G Nussdorfer.   

Abstract

The mechanism underlying cytogenesis in the adrenal cortex of ACTH-treated rats was investigated. ACTH was found to increase the number of parenchymal cells in the zona fasciculata as well as that of "S" phase cells in the inner half of the zona glomerulosa and in the outer third of the zona fasciculata. The fate of 3H-thymidine labelled cells in ACTH-administered rats was also autoradiographically followed. The results are consistent with the hypothesis that the ACTH-provoked hyperplasia in the zona fasciculata involves the centripetal migration of newly-formed parenchymal cells from the zona glomerulosa.

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Year:  1978        PMID: 227327

Source DB:  PubMed          Journal:  Arch Anat Histol Embryol        ISSN: 0249-5554


  4 in total

1.  Comparative stereological studies on the effects of long term CRF and ACTH treatment on the cortex of the suprarenal gland.

Authors:  B Miśkowiak; A Kasprzak; L K Malendowicz
Journal:  J Anat       Date:  1986-06       Impact factor: 2.610

2.  Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.

Authors:  Isabelle Sahut-Barnola; Cyrille de Joussineau; Pierre Val; Sarah Lambert-Langlais; Christelle Damon; Anne-Marie Lefrançois-Martinez; Jean-Christophe Pointud; Geoffroy Marceau; Vincent Sapin; Frédérique Tissier; Bruno Ragazzon; Jérôme Bertherat; Lawrence S Kirschner; Constantine A Stratakis; Antoine Martinez
Journal:  PLoS Genet       Date:  2010-06-10       Impact factor: 5.917

3.  Sex differences in adrenocortical structure and function. XI. Autoradiographic studies on cell proliferation and turnover in the adrenal cortex of the male and female rat and its dependence on testosterone and estradiol.

Authors:  L K Malendowicz; B Jachimowicz
Journal:  Cell Tissue Res       Date:  1982       Impact factor: 5.249

4.  Epimedium flavonoids counteract the side effects of glucocorticoids on hypothalamic-pituitary-adrenal axis.

Authors:  Jianhua Huang; Jijun Li; Songbai Zheng; Junzhen Wu; Wei Zhang; Tao Sun; Sheilesh Kumar Dewan; Bill Kalionis; Ziyin Shen; Xiantao Tai; Shijin Xia
Journal:  Evid Based Complement Alternat Med       Date:  2013-09-23       Impact factor: 2.629

  4 in total

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