| Literature DB >> 22732671 |
Carmen Mariana Chifiriuc1, Alexandru Mihai Grumezescu, Crina Saviuc, Cristina Croitoru, Dan Eduard Mihaiescu, Veronica Lazar.
Abstract
During the present study, we have evaluated magnetic chitosan as a potential drug delivery device, by specifically determining if chitosan could elute antibiotics in an active form that would be efficacious in inhibiting Staphylococcus aureus and Escherichia coli growth. We have demonstrated that the incorporation of cephalosporins of second, third and fourth generation into magnetic chitosan microspheres can possibly lead to an improved delivery of antibiotics in active forms, probably due to the inherent properties of chitosan.Entities:
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Year: 2012 PMID: 22732671 DOI: 10.1016/j.ijpharm.2012.06.031
Source DB: PubMed Journal: Int J Pharm ISSN: 0378-5173 Impact factor: 5.875