BACKGROUND: Accurate coronary artery calcium scoring improves risk stratification in some strata of the population. OBJECTIVE: We evaluated individual and combined effects of reader experience, heart rate, vessel displacement, and trajectory on computed tomography (CT) Agatston score, calcium volume, and calcium mass in a cardiac phantom model. METHODS: A cardiac motion phantom was scanned with a 64-slice CT scanner with artificial electrocardiogram gating with combinations of the following: heart rates 60, 80, and 100 beat/min; vessel displacement of 1.25 and 2.5 cm; and multiple vessel trajectories of craniocaudal, right-left, anteroposterior, right coronary artery (RCA), left anterior descending, and left circumflex (LCX). Calcium quantification was done by 2 different readers with the use of 3 methods: Agatston, calcium volume, and calcium mass. RESULTS: Heart rate, coronary displacement, and trajectory had significant effects on all 3 techniques, with a general decrease in score as the heart rate increased. A vessel displacement of 2.5 cm decreased the Agatston score by 16% (P < 0.0001) and LCX motion decreased the score by 17% (P < 0.0001). Combined effects often resulted in larger differences; for example, a heart rate of 60 beat/min, vessel displacement of 1.25 cm, and RCA motion resulted in an Agatston score of 907, whereas with a heart rate of 100 beat/min, vessel displacement of 2.5 cm, and LCX motion the score was 604. CONCLUSION: The calcium score is affected by heart rate, vessel displacement, and trajectory.
BACKGROUND: Accurate coronary artery calcium scoring improves risk stratification in some strata of the population. OBJECTIVE: We evaluated individual and combined effects of reader experience, heart rate, vessel displacement, and trajectory on computed tomography (CT) Agatston score, calcium volume, and calcium mass in a cardiac phantom model. METHODS: A cardiac motion phantom was scanned with a 64-slice CT scanner with artificial electrocardiogram gating with combinations of the following: heart rates 60, 80, and 100 beat/min; vessel displacement of 1.25 and 2.5 cm; and multiple vessel trajectories of craniocaudal, right-left, anteroposterior, right coronary artery (RCA), left anterior descending, and left circumflex (LCX). Calcium quantification was done by 2 different readers with the use of 3 methods: Agatston, calcium volume, and calcium mass. RESULTS: Heart rate, coronary displacement, and trajectory had significant effects on all 3 techniques, with a general decrease in score as the heart rate increased. A vessel displacement of 2.5 cm decreased the Agatston score by 16% (P < 0.0001) and LCX motion decreased the score by 17% (P < 0.0001). Combined effects often resulted in larger differences; for example, a heart rate of 60 beat/min, vessel displacement of 1.25 cm, and RCA motion resulted in an Agatston score of 907, whereas with a heart rate of 100 beat/min, vessel displacement of 2.5 cm, and LCX motion the score was 604. CONCLUSION: The calcium score is affected by heart rate, vessel displacement, and trajectory.
Authors: N R van der Werf; M J Willemink; T P Willems; R Vliegenthart; M J W Greuter; T Leiner Journal: Int J Cardiovasc Imaging Date: 2017-12-28 Impact factor: 2.357
Authors: Niels R van der Werf; Marcel J W Greuter; Ronald Booij; Aad van der Lugt; Ricardo P J Budde; Marcel van Straten Journal: Eur Radiol Date: 2022-03-01 Impact factor: 7.034
Authors: Niels R van der Werf; Margo van Gent; Ronald Booij; Daniel Bos; Aad van der Lugt; Ricardo P J Budde; Marcel J W Greuter; Marcel van Straten Journal: Diagnostics (Basel) Date: 2021-11-25