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Literature DB >> 22730527

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency.

Philip R Taylor, Dagmar Heydeck, Gareth W Jones, Gerhard Krönke, Colin D Funk, Steven Knapper, Deborah Adams, Hartmut Kühn, Valerie B O'Donnell.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2012 PMID： 22730527 PMCID： PMC3392071 DOI： 10.1182/blood-2012-02-410928

Source DB: PubMed Journal: Blood ISSN： 0006-4971 Impact factor: 25.476

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4 in total

1. Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.

Authors: Michelle Kinder; James E Thompson; Cong Wei; Suresh G Shelat; Ian A Blair; Martin Carroll; Ellen Puré
Journal: Exp Hematol Date: 2010-07-18 Impact factor: 3.084

2. Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein.

Authors: D Sun; C D Funk
Journal: J Biol Chem Date: 1996-09-27 Impact factor: 5.157

3. Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism.

Authors: Michelle Kinder; Cong Wei; Suresh G Shelat; Mondira Kundu; Liang Zhao; Ian A Blair; Ellen Puré
Journal: Blood Date: 2010-03-31 Impact factor: 22.113

4. Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease.

Authors: Melissa Kristine Middleton; Alicia Marie Zukas; Tanya Rubinstein; Michele Jacob; Peijuan Zhu; Liang Zhao; Ian Blair; Ellen Puré
Journal: J Exp Med Date: 2006-10-16 Impact factor: 14.307

4 in total

5 in total

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency.

1. Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.

2. Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein.

3. Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism.

4. Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease.

Review 1. 12/15-lipoxygenase during the regulation of inflammation, immunity, and self-tolerance.

2. The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal.

3. Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo.

Review 4. Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling.

5. A novel role for 12/15-lipoxygenase in regulating autophagy.