Geoffroy Dequirez1, Valérie Pons, Philippe Dauban. 1. Centre de Recherche de Gif-sur-Yvette, Institut de Chimie des Substances Naturelles, UPR 2301 CNRS, Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
Abstract
The element nitrogen is essential to life. Considerable attention is thus paid to the development of synthetic methods for its introduction into molecules. Nitrenes, long regarded as highly reactive but poorly selective species, have recently emerged as useful tools for the formation of C-N bonds. Practical metal-catalyzed protocols are now available for the preparation of amines through either the aziridination of alkenes or the C-H amination of alkanes. Recent results highlighted in this Minireview suggest that synthetic nitrene chemistry is maturing with a wider scope not limited to these two reactions.
The element nitrogen is essential to life. Considerable attention is thus paid to the development of synthetic methods for its introduction into molecules. n class="Chemical">Nitrenes, long regarded as highly reactive but poorly selective species, have recently emerged as useful tools for the formation of C-N bonds. Practical metal-catalyzed protocols are now available for the preparation of amines through either the aziridination of alkenes or the C-H amination of alkanes. Recent results highlighted in this Minireview suggest that synthetic nitrene chemistry is maturing with a wider scope not limited to these two reactions.
Authors: Xin Hong; Daniel A Bercovici; Zhongyue Yang; Nezar Al-Bataineh; Ramya Srinivasan; Ram C Dhakal; K N Houk; Matthias Brewer Journal: J Am Chem Soc Date: 2015-07-07 Impact factor: 15.419
Authors: Minxue Huang; Tzuhsiung Yang; Jonathan D Paretsky; John F Berry; Jennifer M Schomaker Journal: J Am Chem Soc Date: 2017-11-20 Impact factor: 15.419
Authors: Nicholas S Dolan; Ryan J Scamp; Tzuhsiung Yang; John F Berry; Jennifer M Schomaker Journal: J Am Chem Soc Date: 2016-10-26 Impact factor: 15.419
Authors: Jared W Rigoli; Cale D Weatherly; Juliet M Alderson; Brian T Vo; Jennifer M Schomaker Journal: J Am Chem Soc Date: 2013-11-11 Impact factor: 15.419