Literature DB >> 22729663

Reconstruction of iliac crest with bovine cancellous allograft after bone graft harvest for symphysis pubis arthrodesis.

Konstantinos G Makridis1, Mudussar Abrar Ahmad, Nikolaos K Kanakaris, Evangelos M Fragkakis, Peter V Giannoudis.   

Abstract

PURPOSE: The aim of this study was to evaluate the safety and efficiency, as well as the incorporation characteristics of a specific type of xenograft used for iliac crest defects post-harvesting tri-cortical iliac crest bone graft.
METHODS: Sixteen patients diagnosed with chronic anterior pelvic pain were operated for pubic symphysis fusion. The tri-cortical graft harvested from the iliac crest was inserted into the pubic symphysis and compressed with a reconstruction plate. The defect in the iliac crest was filled with a block of cancellous bovine substitute (Tutobone®). The length of iliac crest defect, time to fusion of pubic symphysis, time to incorporation of the graft and complications were recorded. The postoperative pain and patients' satisfaction were evaluated.
RESULTS: The median age of patients was 36.5 years (range 27-75). Fusion was obtained in 15 patients (94 %). The median time to fusion was four months (range three to seven). The length of the iliac crest bone defect ranged from 40 to 70 mm. Integration of the bovine substitute was achieved in 15 patients (94 %) over a median period of three months (range two to six). The postoperative median pain score was 2 (range 1-5). Twelve patients (75 %) reported good satisfaction. No major complications or allergic reactions were observed.
CONCLUSIONS: The xenograft used in this study provided a safe and effective method of reconstruction of iliac crest donor site defects. It has satisfactory incorporation, high biocompatibility and no signs of inflammatory reactions. This new technique is simple and easily reproducible in routine clinical practice.

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Year:  2012        PMID: 22729663      PMCID: PMC3535019          DOI: 10.1007/s00264-012-1572-z

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  33 in total

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Review 4.  Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review.

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7.  Reconstruction of anterior iliac crest bone graft donor sites: presentation of a surgical technique.

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Authors:  Nikolaos K Kanakaris; Craig S Roberts; Peter V Giannoudis
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4.  Biomechanical analysis of iliac crest loading following cortico-cancellous bone harvesting.

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5.  Reconstruction of iliac crest defect after autogenous harvest with bone cement and screws reduces donor site pain.

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6.  Study of Two Bovine Bone Blocks (Sintered and Non-Sintered) Used for Bone Grafts: Physico-Chemical Characterization and In Vitro Bioactivity and Cellular Analysis.

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7.  The assessment of xenogeneic bone immunotoxicity and risk management study.

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  7 in total

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