Literature DB >> 22729300

Age influences outcomes in 70-year or older patients undergoing isolated coronary artery bypass graft surgery.

Antônio Sérgio Cordeiro da Rocha1, Felipe José Monassa Pittella, Andrea Rocha de Lorenzo, Valmir Barzan, Alexandre Siciliano Colafranceschi, José Oscar Reis Brito, Marco Antoniode de Mattos, Paulo Roberto Dutra da Silva.   

Abstract

OBJECTIVE: To analyze the results of isolated on-pump coronary artery bypass graft surgery (CABG) in patients >70 years-old in comparison to patients <70 years-old.
METHODS: Patients undergoing isolated CABG were selected for the study. The patients were grouped in G1 (age > 70 years-old) and G2 (age <70 years-old). The endpoints were in-hospital mortality, acute myocardial infarction (AMI), stroke, reexploration for bleeding, intra-aortic balloon for circulatory shock, respiratory complications, acute renal failure, mediastinitis, sepsis, atrial fibrillation, and complete atrioventricular block (CAVB).
RESULTS: 1,033 patients were included, 257 (24.8%) in G1 and 776 (75.2%) in G2. Patients in G1 were more likely to have in-hospital mortality than G2 (8.9% vs. 3.6%, respectively; P=0.001), while the incidence of AMI was similar (5.8% vs. 5.5%; P=0.87) than G2. More patients in G1 had re-exploration for bleeding (12.1% vs. 6.1%; P=0.003). G1 had more incidence of respiratory complications (21.4% vs. 9.1%; P<0.001), mediastinitis (5.1% vs. 1.9%; P=0.013), stroke (3.9% vs. 1.3%; P=0.016), acute renal failure (7.8% vs. 1.3%; P<0.001), sepsis (3.9% vs. 1.9%;P=0.003), atrial fibrillation (15.6% vs. 9.8%; P=0.016), and CAVB (3.5% vs. 1.2%; P=0.023) than G2. There was no significant difference in the use of intra-aortic balloon. In the forward stepwise multivariate logistic regression analysis age > 70-year-old was an independent predictive factor for higher in-hospital mortality (P=0.004), reexploration for bleeding (P=0.002), sepsis (P=0.002), respiratory complications (P<0.001), mediastinitis (P=0.016), stroke (P=0.029), acute renal failure (P<0.001), atrial fibrillation (P=0.021) and CAVB (P=0.031).
CONCLUSION: This study suggests that patients > 70 years-old were at increased risk of death and other complications in the CABG's postoperative period in comparison to younger patients.

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Year:  2012        PMID: 22729300     DOI: 10.5935/1678-9741.20120008

Source DB:  PubMed          Journal:  Rev Bras Cir Cardiovasc


  7 in total

1.  Atrioventricular block in coronary artery bypass surgery: perioperative predictors and impact on mortality.

Authors:  Ricardo Medeiros Piantá; Andres Di Leoni Ferrari; Aline Almeida Heck; Débora Klein Ferreira; Jacqueline da Costa Escobar Piccoli; Luciano Cabral Albuquerque; João Carlos Vieira da Costa Guaragna; João Batista Petracco
Journal:  Rev Bras Cir Cardiovasc       Date:  2015 Mar-Apr

2.  The effect of gender on the early results of coronary artery bypass surgery in the younger patients' group.

Authors:  Hasan Uncu; Mehmet Acipayam; Levent Altinay; Pinar Doğan; Isil Davarcı; İbrahim Özsöyler
Journal:  Rev Bras Cir Cardiovasc       Date:  2014 Oct-Dec

3.  Risk factors for mortality of patients undergoing coronary artery bypass graft surgery.

Authors:  Carlos Alberto Dos Santos; Marcos Aurélio Barboza de Oliveira; Antônio Carlos Brandi; Paulo Henrique Husseini Botelho; Josélia de Cássia Menin Brandi; Marcio Antônio Dos Santos; Moacir Fernandes de Godoy; Domingo Marcolino Braile
Journal:  Rev Bras Cir Cardiovasc       Date:  2014 Oct-Dec

4.  New-onset of postoperative atrial fibrillation is likely to recur in the absence of other triggers.

Authors:  Jesper Park-Hansen; Anders M Greve; Johan Clausen; Susanne J Holme; Christian L Carranza; Akhmadjon Irmukhamedov; Lubna Sabah; Qing Lin; Anne Sofie Madsen; Helena Domínguez
Journal:  Ther Clin Risk Manag       Date:  2018-09-07       Impact factor: 2.423

5.  Rotablation in the treatment of high-risk patients with heavily calcified left-main coronary lesions.

Authors:  Meng-Hsiu Chiang; Hung-Tao Yi; Cheng-Rong Tsao; Wei-Chun Chang; Chieh-Shou Su; Tsun-Jui Liu; Kae-Woei Liang; Chih-Tai Ting; Wen-Lieng Lee
Journal:  J Geriatr Cardiol       Date:  2013-09       Impact factor: 3.327

Review 6.  Percutaneous Coronary Intervention in Elderly Patients with Coronary Chronic Total Occlusions: Current Evidence and Future Perspectives.

Authors:  Lei Guo; Hai-Chen Lv; Rong-Chong Huang
Journal:  Clin Interv Aging       Date:  2020-05-28       Impact factor: 4.458

7.  Validation of EuroSCORE II in patients undergoing coronary artery bypass grafting (CABG) surgery at the National Heart Institute, Kuala Lumpur: a retrospective review.

Authors:  Ahmad Farouk Musa; Xian Pei Cheong; Jeswant Dillon; Rusli Bin Nordin
Journal:  F1000Res       Date:  2018-05-02
  7 in total

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