Literature DB >> 22728932

Lighting the fat furnace without SFRP5.

Alexander Rauch, Susanne Mandrup.   

Abstract

WNT signaling plays a central role in the regulation of cellular growth and differentiation. In this issue of the JCI, Mori et al. link WNT signaling to the oxidative capacity of adipocytes during obesity. They show that secreted frizzled-related protein 5 is an extracellular matrix-residing protein that is highly induced during obesity and inhibits oxidative phosphorylation in a tissue-autonomous manner, possibly by sequestering WNT3a. These results implicate local WNT signaling as an attractive target for combating obesity.

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Year:  2012        PMID： 22728932      PMCID： PMC3386836          DOI： 10.1172/JCI64196

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  22 in total

1.  Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.

Authors:  Luca Grumolato; Guizhong Liu; Phyllus Mong; Raksha Mudbhary; Romi Biswas; Randy Arroyave; Sapna Vijayakumar; Aris N Economides; Stuart A Aaronson
Journal:  Genes Dev       Date:  2010-11-15       Impact factor: 11.361

2.  Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.

Authors:  Rasmus Siersbæk; Ronni Nielsen; Sam John; Myong-Hee Sung; Songjoon Baek; Anne Loft; Gordon L Hager; Susanne Mandrup
Journal:  EMBO J       Date:  2011-03-22       Impact factor: 11.598

Review 3.  Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.

Authors:  Paola Bovolenta; Pilar Esteve; Jose Maria Ruiz; Elsa Cisneros; Javier Lopez-Rios
Journal:  J Cell Sci       Date:  2008-03-15       Impact factor: 5.285

4.  COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.

Authors:  Masashi Okamura; Hiromi Kudo; Ken-ichi Wakabayashi; Toshiya Tanaka; Aya Nonaka; Aoi Uchida; Shuichi Tsutsumi; Iori Sakakibara; Makoto Naito; Timothy F Osborne; Takao Hamakubo; Sadayoshi Ito; Hiroyuki Aburatani; Masashi Yanagisawa; Tatsuhiko Kodama; Juro Sakai
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-23       Impact factor: 11.205

5.  Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis.

Authors:  Ronni Nielsen; Thomas Askov Pedersen; Dik Hagenbeek; Panagiotis Moulos; Rasmus Siersbaek; Eva Megens; Sergei Denissov; Michael Børgesen; Kees-Jan Francoijs; Susanne Mandrup; Hendrik G Stunnenberg
Journal:  Genes Dev       Date:  2008-11-01       Impact factor: 11.361

Review 6.  Wnt5a: its signalling, functions and implication in diseases.

Authors:  A Kikuchi; H Yamamoto; A Sato; S Matsumoto
Journal:  Acta Physiol (Oxf)       Date:  2011-04-22       Impact factor: 6.311

7.  Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity.

Authors:  Noriyuki Ouchi; Akiko Higuchi; Koji Ohashi; Yuichi Oshima; Noyan Gokce; Rei Shibata; Yuichi Akasaki; Akihiko Shimono; Kenneth Walsh
Journal:  Science       Date:  2010-06-17       Impact factor: 47.728

8.  Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling.

Authors:  Yan Li; Scott A Rankin; Débora Sinner; Alan P Kenny; Paul A Krieg; Aaron M Zorn
Journal:  Genes Dev       Date:  2008-11-01       Impact factor: 11.361

9.  Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network.

Authors:  Claire Lagathu; Constantinos Christodoulides; Sam Virtue; William P Cawthorn; Chiara Franzin; Wendy A Kimber; Edoardo Dalla Nora; Mark Campbell; Gema Medina-Gomez; Benjamin N R Cheyette; Antonio J Vidal-Puig; Jaswinder K Sethi
Journal:  Diabetes       Date:  2008-12-10       Impact factor: 9.461

10.  PIPs: human protein-protein interaction prediction database.

Authors:  Mark D McDowall; Michelle S Scott; Geoffrey J Barton
Journal:  Nucleic Acids Res       Date:  2008-11-06       Impact factor: 16.971
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  6 in total

1.  Recombinant SFRP5 protein significantly alleviated intrahepatic inflammation of nonalcoholic steatohepatitis.

Authors:  Lili Chen; Xiaolong Zhao; Guangjun Liang; Jiuru Sun; Zhifeng Lin; Renming Hu; Peili Chen; Zhaoyun Zhang; Linuo Zhou; Yiming Li
Journal:  Nutr Metab (Lond)       Date:  2017-08-15       Impact factor: 4.169

Review 2.  Secreted Frizzled Related Proteins in Cardiovascular and Metabolic Diseases.

Authors:  Hua Guan; Jin Zhang; Jing Luan; Hao Xu; Zhenghao Huang; Qi Yu; Xingchun Gou; Lixian Xu
Journal:  Front Endocrinol (Lausanne)       Date:  2021-08-20       Impact factor: 5.555

3.  Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity.

Authors:  Laia Bertran; Marta Portillo-Carrasquer; Andrea Barrientos-Riosalido; Carmen Aguilar; David Riesco; Salomé Martínez; Amada Culebradas; Margarita Vives; Fàtima Sabench; Daniel Del Castillo; Cristóbal Richart; Teresa Auguet
Journal:  Int J Mol Sci       Date:  2022-08-30       Impact factor: 6.208

4.  Deregulation of Secreted Frizzled-Related Protein 5 in Nonalcoholic Fatty Liver Disease Associated with Obesity.

Authors:  Laia Bertran; Marta Portillo-Carrasquer; Carmen Aguilar; José Antonio Porras; David Riesco; Salomé Martínez; Margarita Vives; Fàtima Sabench; Eva Gonzalez; Daniel Del Castillo; Cristóbal Richart; Teresa Auguet
Journal:  Int J Mol Sci       Date:  2021-06-27       Impact factor: 5.923

5.  Decaffeinated green coffee bean extract attenuates diet-induced obesity and insulin resistance in mice.

Authors:  Su Jin Song; Sena Choi; Taesun Park
Journal:  Evid Based Complement Alternat Med       Date:  2014-04-10       Impact factor: 2.629

6.  Umbilical Cord SFRP5 Levels of Term Newborns in Relation to Normal and Excessive Gestational Weight Gain.

Authors:  Żaneta Kimber-Trojnar; Jolanta Patro-Małysza; Marcin Trojnar; Dorota Darmochwał-Kolarz; Jan Oleszczuk; Bożena Leszczyńska-Gorzelak
Journal:  Int J Mol Sci       Date:  2019-01-30       Impact factor: 5.923
  6 in total

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