BACKGROUND: REM sleep behavior disorder (RBD) is common in Parkinson's disease (PD). While previous studies of idiopathic RBD have reported a striking male preponderance, little information exists about potential gender differences of RBD in PD. METHODS: We performed a cross sectional study of 107 PD patients. Probable RBD (pRBD) was diagnosed using the RBD Screening Questionnaire. RESULTS: Men had more fights (96% versus 54%, p < 0.001), violent behavior (71% versus 39%, p = 0.04) and awakening by own movements (89% versus 62%, p = 0.04). More women experienced disturbed sleep (85% versus 32%, p = 0.02). The frequency of pRBD was 31% in women and 43% in men (p = 0.2), total frequency 38%. CONCLUSIONS: We found no clear differences in the frequency of pRBD among men and women with PD, but demonstrated significant gender differences in its clinical expression. Female PD patients reported significantly less fights and aggressive behavior during dreams, but had more disturbed sleep.
BACKGROUND:REM sleep behavior disorder (RBD) is common in Parkinson's disease (PD). While previous studies of idiopathic RBD have reported a striking male preponderance, little information exists about potential gender differences of RBD in PD. METHODS: We performed a cross sectional study of 107 PDpatients. Probable RBD (pRBD) was diagnosed using the RBD Screening Questionnaire. RESULTS:Men had more fights (96% versus 54%, p < 0.001), violent behavior (71% versus 39%, p = 0.04) and awakening by own movements (89% versus 62%, p = 0.04). More women experienced disturbed sleep (85% versus 32%, p = 0.02). The frequency of pRBD was 31% in women and 43% in men (p = 0.2), total frequency 38%. CONCLUSIONS: We found no clear differences in the frequency of pRBD among men and women with PD, but demonstrated significant gender differences in its clinical expression. Female PDpatients reported significantly less fights and aggressive behavior during dreams, but had more disturbed sleep.
Authors: Marina Picillo; Marianna Amboni; Roberto Erro; Katia Longo; Carmine Vitale; Marcello Moccia; Angela Pierro; Gabriella Santangelo; Anna De Rosa; Giuseppe De Michele; Lucio Santoro; Giuseppe Orefice; Paolo Barone; Maria Teresa Pellecchia Journal: J Neurol Date: 2013-08-30 Impact factor: 4.849
Authors: Stuart J McCarter; Erik K St Louis; Christopher L Boswell; Lucas G Dueffert; Nancy Slocumb; Bradley F Boeve; Michael H Silber; Eric J Olson; Timothy I Morgenthaler; Maja Tippmann-Peikert Journal: Sleep Med Date: 2014-06-23 Impact factor: 3.492