| Literature DB >> 22723098 |
Abstract
In 2006, panitumumab, the first fully human antibody generated from transgenic mice, was approved for clinical use by the US Food and Drug Administration (FDA). Since then, a further seven such antibodies have been approved. In this chapter, we discuss how transgenic mice technologies can provide a powerful platform for creating human therapeutic antibodies.Entities:
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Year: 2012 PMID： 22723098 DOI： 10.1007/978-1-61779-931-0_8
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745