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Literature DB >> 22722820

Histone deacetylases in kidney development: implications for disease and therapy.

Abstract

Histone deacetylases (HDACs) are an evolutionarily conserved group of enzymes that regulate a broad range of biological processes through removal of acetyl groups from histones as well as non-histone proteins. Recent studies using a variety of pharmacological inhibitors and genetic models of HDACs have revealed a central role of HDACs in control of kidney development. These findings provide new insights into the epigenetic mechanisms underlying congenital anomalies of the kidney and urinary tract (CAKUT) and implicate the potential of HDACs as therapeutic targets in kidney diseases, such as cystic kidney diseases and renal cell cancers. Determining the specific functions of individual HDAC members would be an important task of future research.

Entities: Disease

Mesh：

Substances：

Year: 2012 PMID： 22722820 DOI： 10.1007/s00467-012-2223-8

Source DB: PubMed Journal: Pediatr Nephrol ISSN： 0931-041X Impact factor: 3.714

65 in total

1. A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

Authors: U Dressel; P J Bailey; S C Wang; M Downes; R M Evans; G E Muscat
Journal: J Biol Chem Date: 2001-03-08 Impact factor: 5.157

Review 2. A shifting paradigm: histone deacetylases and transcriptional activation.

Authors: Catharine L Smith
Journal: Bioessays Date: 2008-01 Impact factor: 4.345

3. Inhibition of histone deacetylase expands the renal progenitor cell population.

Authors: Eric D de Groh; Lisa M Swanhart; Chiara Cianciolo Cosentino; Rachel L Jackson; Weixiang Dai; Carolyn A Kitchens; Billy W Day; Thomas E Smithgall; Neil A Hukriede
Journal: J Am Soc Nephrol Date: 2010-04-08 Impact factor: 10.121

Review 4. Histone deacetylases (HDACs): characterization of the classical HDAC family.

Authors: Annemieke J M de Ruijter; Albert H van Gennip; Huib N Caron; Stephan Kemp; André B P van Kuilenburg
Journal: Biochem J Date: 2003-03-15 Impact factor: 3.857

5. Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family.

Authors: Lin Gao; Maria A Cueto; Fred Asselbergs; Peter Atadja
Journal: J Biol Chem Date: 2002-04-10 Impact factor: 5.157

Review 6. Renal abnormalities and their developmental origin.

Authors: Andreas Schedl
Journal: Nat Rev Genet Date: 2007-10 Impact factor: 53.242

Review 7. Cell and molecular biology of kidney development.

Authors: Kimberly J Reidy; Norman D Rosenblum
Journal: Semin Nephrol Date: 2009-07 Impact factor: 5.299

8. The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo.

Authors: Flavio Leoni; Gianluca Fossati; Eli C Lewis; Jae-Kwon Lee; Giulia Porro; Paolo Pagani; Daniela Modena; Maria Lusia Moras; Pietro Pozzi; Leonid L Reznikov; Britta Siegmund; Giamila Fantuzzi; Charles A Dinarello; Paolo Mascagni
Journal: Mol Med Date: 2005 Jan-Dec Impact factor: 6.354

9. HDAC2 negatively regulates memory formation and synaptic plasticity.

Authors: Ji-Song Guan; Stephen J Haggarty; Emanuela Giacometti; Jan-Hermen Dannenberg; Nadine Joseph; Jun Gao; Thomas J F Nieland; Ying Zhou; Xinyu Wang; Ralph Mazitschek; James E Bradner; Ronald A DePinho; Rudolf Jaenisch; Li-Huei Tsai
Journal: Nature Date: 2009-05-07 Impact factor: 49.962

10. Histone deacetylase inhibitors as novel anticancer therapeutics.

Authors: D R Walkinshaw; X J Yang
Journal: Curr Oncol Date: 2008-10 Impact factor: 3.677

10 in total

1. TGF-β induces miR-30d down-regulation and podocyte injury through Smad2/3 and HDAC3-associated transcriptional repression.

Authors: Lin Liu; Wenjun Lin; Qin Zhang; Wangsen Cao; Zhihong Liu
Journal: J Mol Med (Berl) Date: 2015-10-03 Impact factor: 4.599

Review 2. Histone Deacetylases in Kidney Physiology and Acute Kidney Injury.

Authors: Kelly A Hyndman
Journal: Semin Nephrol Date: 2020-03 Impact factor: 5.299

Review 3. Histone deacetylase 3 (HDAC3) as an important epigenetic regulator of kidney diseases.

Authors: Lijun Zhang; Wangsen Cao
Journal: J Mol Med (Berl) Date: 2021-10-26 Impact factor: 4.599

4. Vorinostat protects against calcium oxalate-induced kidney injury in mice.

Authors: Li Wang; Wei Chen; Zhongjiang Peng; Changcheng Liu; Caihong Zhang; Zhiyong Guo
Journal: Mol Med Rep Date: 2015-06-19 Impact factor: 2.952

Review 5. Treatment of chronic kidney diseases with histone deacetylase inhibitors.

Authors: Na Liu; Shougang Zhuang
Journal: Front Physiol Date: 2015-04-28 Impact factor: 4.566

Review 6. Epigenetics of Renal Development and Disease.

Authors: Sylvia A Hilliard; Samir S El-Dahr
Journal: Yale J Biol Med Date: 2016-12-23

7. Valproic acid restores the down-regulation of SDF-1 following kidney ischemia; experimental validation of a mathematical prediction.

Authors: Kobra Moradzadeh; Seyed Mahdi Nassiri; Yousof Gheisari
Journal: Res Pharm Sci Date: 2020-05-11