Literature DB >> 22722740

New alkyl-phosphate bonded stationary phases for liquid chromatographic separation of biologically active compounds.

Szymon Bocian1, Alicja Nowaczyk, Boguslaw Buszewski.   

Abstract

A new type of bonded stationary phase for liquid chromatography, with the properties of immobilized artificial membranes, has been synthesized. Alkyl-phosphate adsorbents were obtained by modification of aminopropyl silica gel. The structures of the synthesized materials were confirmed by use of instrumental techniques--elemental analysis, infrared spectroscopy (FTIR), and (13)C and (29)Si CP/MAS NMR. Analysis revealed that the adsorbents mimic the phospholipids present in natural cell membranes. The new synthesized alkyl-phosphate stationary phases may be used for liquid chromatographic separation of biologically active compounds of different polarity.

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Year:  2012        PMID： 22722740      PMCID： PMC3407363          DOI： 10.1007/s00216-012-6134-0

Source DB:  PubMed          Journal:  Anal Bioanal Chem        ISSN： 1618-2642            Impact factor:   4.142


  15 in total

Review 1.  Immobilized artificial membrane HPLC in drug research.

Authors:  Agnes Taillardat-Bertschinger; Pierre-Alain Carrupt; Francesco Barbato; Bernard Testa
Journal:  J Med Chem       Date:  2003-02-27       Impact factor: 7.446

Review 2.  Characterizing HPLC stationary phases.

Authors:  Katarzyna Krupczyńska; Bogusław Buszewski; Pavel Jandera
Journal:  Anal Chem       Date:  2004-07-01       Impact factor: 6.986

3.  Artifacts in liquid-phase separations-system, solvent, and impurity peaks.

Authors:  Boguslaw Buszewski; Szymon Bocian; Attila Felinger
Journal:  Chem Rev       Date:  2012-02-06       Impact factor: 60.622

4.  Chemically bonded phases for the reversed-phase high-performance liquid chromatographic separation of basic substances.

Authors:  B Buszewski; J Schmid; K Albert; E Bayer
Journal:  J Chromatogr       Date:  1991-08-09

5.  Determination of selected beta-receptor antagonists in biological samples by solid-phase extraction with cholesterolic phase and LC/MS.

Authors:  Bogusław Buszewski; Tomasz Welerowicz; Eugenia Tegowska; Tadeusz F Krzemiński
Journal:  Anal Bioanal Chem       Date:  2008-09-11       Impact factor: 4.142

6.  Cholesteric bonded stationary phases for high-performance liquid chromatography: synthesis, physicochemical characterization, and chromatographic behavior of a phospho-cholesteric bonded support. A new way to mimic drug/membrane interactions?

Authors:  Cédric Courtois; Christophe Allais; Thierry Constantieux; Jean Rodriguez; Stefano Caldarelli; Corinne Delaurent
Journal:  Anal Bioanal Chem       Date:  2008-10-08       Impact factor: 4.142

7.  Synthesis and characterization of endcapped C18 stationary phases using a silica hydride intermediate.

Authors:  Joseph J Pesek; Maria T Matyska; Raymond J Yu
Journal:  J Chromatogr A       Date:  2002-02-22       Impact factor: 4.759

8.  Phospholipid immobilization on solid surfaces.

Authors:  S Ong; S J Cai; C Bernal; D Rhee; X Qiu; C Pidgeon
Journal:  Anal Chem       Date:  1994-03-15       Impact factor: 6.986

9.  Predicting drug-membrane interactions by HPLC: structural requirements of chromatographic surfaces.

Authors:  H Liu; S Ong; L Glunz; C Pidgeon
Journal:  Anal Chem       Date:  1995-10-01       Impact factor: 6.986

10.  Cholesteric bonded stationary phases for high-performance liquid chromatography: a comparative study of the chromatographic behavior.

Authors:  Cédric Courtois; Guilhem Pagès; Stefano Caldarelli; Corinne Delaurent
Journal:  Anal Bioanal Chem       Date:  2008-07-24       Impact factor: 4.142
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  2 in total

1.  Validation of an RPHPTLC-Densitometric Method Using Silica Gel 60 RP18WF254 for Simultaneous Determination of Nicotinamide in Selected Pharmaceutical Formulations.

Authors:  Małgorzata Dołowy; Alina Pyka
Journal:  J Anal Methods Chem       Date:  2015-03-05       Impact factor: 2.193

Review 2.  Stationary Phases for Green Liquid Chromatography.

Authors:  Mikołaj Dembek; Szymon Bocian
Journal:  Materials (Basel)       Date:  2022-01-06       Impact factor: 3.623
  2 in total

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