Literature DB >> 22722394

Signalling. A new role for MYC?

Serena Tan1.   

Abstract

Liu et al. have identified MYC as a suppressor of metastasis, cell motility and invasion, and provide evidence that this newly uncovered role is dependent on the αv and β3 integrin extracellular matrix receptors.

Entities:  

Year:  2012        PMID: 22722394     DOI: 10.1038/nrc3308

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN: 1474-175X            Impact factor:   60.716


  1 in total

1.  MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits.

Authors:  Hong Liu; Derek C Radisky; Dun Yang; Ren Xu; Evette S Radisky; Mina J Bissell; J Michael Bishop
Journal:  Nat Cell Biol       Date:  2012-05-13       Impact factor: 28.824

  1 in total

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