Literature DB >> 22721977

Tendon coverage using an artificial skin substitute.

Jaimie T Shores1, Matthew Hiersche, Allen Gabriel, Subhas Gupta.   

Abstract

BACKGROUND: Soft tissue deficits associated with exposed tendon and absent paratenon pose difficult reconstructive problems due to tendon adhesions, poor range of motion, poor cosmesis, and donor site morbidity. Integra Bilayer Matrix Wound Dressing (Integra Lifesciences Corp Plainsboro, NJ) is a skin substitute widely used in reconstructive surgery, including the incidental coverage of tendons. However, Integra's post-operative functionality of the tendons has not been well documented. We report the results of using Integra for soft tissue reconstruction overlying tendons with loss of paratenon in upper and lower extremity soft tissue defects.
METHODS: Forty-two patients (35 men and 7 women) with exposed tendons due to trauma (37), cancer excision (2) or chronic wounds (3) were reconstructed using Integra. Results were compiled in a prospective manner, including age, gender, wound location, wound size, time to final closure, operative time, follow-up length, split-thickness skin graft percentage take and active post-operative range of motion. Likewise using Medline, a literature search of current surgical techniques for the treatment of exposed tendons and the results from the literature were compared with these study results.
RESULTS: All patients healed with an average split-thickness skin graft take rate of 92.5% ± 6.1 (range, 80-100%). The thirty-two patients not lost to follow-up achieved an average range of motion of 91.2% ± 6.5 (range, 80-100%).
CONCLUSION: Integra offers a convenient, efficient operative procedure with minimal morbidity, demonstrating good cosmesis and tendon function. Thus, Integra may offer an alternative option for immediate tendon coverage in both the upper and lower extremities.
Copyright © 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22721977     DOI: 10.1016/j.bjps.2012.05.021

Source DB:  PubMed          Journal:  J Plast Reconstr Aesthet Surg        ISSN: 1748-6815            Impact factor:   2.740


  14 in total

1.  Integra® dermal regenerative template application on exposed tendon.

Authors:  John Hulsen; Ryan Diederich; Michael W Neumeister; Reuben A Bueno
Journal:  Hand (N Y)       Date:  2014-12

2.  Long-term follow-up comparison of two different bi-layer dermal substitutes in tissue regeneration: Clinical outcomes and histological findings.

Authors:  Uberto M Giovannini; Luc Teot
Journal:  Int Wound J       Date:  2020-05-02       Impact factor: 3.315

Review 3.  Use of Biologic Agents in Extremity Reconstruction.

Authors:  Andrew E Grush; Monal Depani; Matthew J Parham; Valeria Mejia-Martinez; Alexandra Thornton; Douglas M Sammer
Journal:  Semin Plast Surg       Date:  2022-04-12       Impact factor: 2.195

4.  Use of Integra in the Management of Complex Hand Wounds From Cancer Resection and Nonburn Trauma.

Authors:  Michael Reynolds; David A Kelly; Nicholas J Walker; Clayton Crantford; Anthony J Defranzo
Journal:  Hand (N Y)       Date:  2017-02-14

5.  Cultivation of keratinocytes and fibroblasts in a three-dimensional bovine collagen-elastin matrix (Matriderm®) and application for full thickness wound coverage in vivo.

Authors:  Jasper Killat; Kerstin Reimers; Claudia Y Choi; Sabrina Jahn; Peter M Vogt; Christine Radtke
Journal:  Int J Mol Sci       Date:  2013-07-11       Impact factor: 5.923

6.  Long-term follow-up of donor site morbidity after defect coverage with Integra following radial forearm flap elevation.

Authors:  Anna Wirthmann; Juliane C Finke; Pietro Giovanoli; Nicole Lindenblatt
Journal:  Eur J Plast Surg       Date:  2014-01-10

Review 7.  Upper limb traumatic injuries: A concise overview of reconstructive options.

Authors:  Marta Starnoni; Elisa Benanti; Andrea Leti Acciaro; Giorgio De Santis
Journal:  Ann Med Surg (Lond)       Date:  2021-05-27

8.  Reconstruction of traumatic defect of the lower third of the leg using a combined therapy: negative pressure wound therapy, acellular dermal matrix, and skin graft.

Authors:  Sergio Brongo; Domenico Pagliara; Nicola Campitiello; Corrado Rubino
Journal:  Case Rep Surg       Date:  2014-08-11

Review 9.  Changing paradigms in lower extremity reconstruction in war-related injuries.

Authors:  Margaret Connolly; Zuhaib R Ibrahim; Owen N Johnson
Journal:  Mil Med Res       Date:  2016-03-31

10.  Use of Hyaluronic Acid-Based Biological Bilaminar Matrix in Wound Bed Preparation: A Case Series.

Authors:  Richard Simman; Walid Mari; Sara Younes; Michael Wilson
Journal:  Eplasty       Date:  2018-04-26
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