OBJECTIVE: To assess differences in gynecologic history and lightheadedness during menstrual cycle phases among patients with POTS and healthy control women. METHODS: In a prospective, questionnaire-based study carried out at Paden Autonomic Dysfunction Center, Vanderbilt University, between April 2005 and January 2009, a custom-designed questionnaire was administered to patients with POTS (n=65) and healthy individuals (n=95). The results were analyzed via Fisher exact test and Mann-Whitney U test. RESULTS: Patients with POTS reported increased lightheadedness through all phases of the menstrual cycle phases as compared with healthy controls. Both groups experienced the greatest lightheadedness during menses, and a decrease in lightheadedness during the follicular phase. Patients with POTS reported a higher incidence of gynecologic diseases as compared with healthy controls. CONCLUSION: The severity of lightheadedness was found to vary during the menstrual cycle, which may relate to changes in estrogen levels. Patients with POTS also reported an increase in estrogen-related gynecologic disease.
OBJECTIVE: To assess differences in gynecologic history and lightheadedness during menstrual cycle phases among patients with POTS and healthy control women. METHODS: In a prospective, questionnaire-based study carried out at Paden Autonomic Dysfunction Center, Vanderbilt University, between April 2005 and January 2009, a custom-designed questionnaire was administered to patients with POTS (n=65) and healthy individuals (n=95). The results were analyzed via Fisher exact test and Mann-Whitney U test. RESULTS:Patients with POTS reported increased lightheadedness through all phases of the menstrual cycle phases as compared with healthy controls. Both groups experienced the greatest lightheadedness during menses, and a decrease in lightheadedness during the follicular phase. Patients with POTS reported a higher incidence of gynecologic diseases as compared with healthy controls. CONCLUSION: The severity of lightheadedness was found to vary during the menstrual cycle, which may relate to changes in estrogen levels. Patients with POTS also reported an increase in estrogen-related gynecologic disease.
Authors: Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde Journal: J Biomed Inform Date: 2008-09-30 Impact factor: 6.317
Authors: Qi Fu; Tiffany B VanGundy; Shigeki Shibata; Richard J Auchus; Gordon H Williams; Benjamin D Levine Journal: Hypertension Date: 2010-05-17 Impact factor: 10.190
Authors: Qi Fu; Tiffany B Vangundy; Shigeki Shibata; Richard J Auchus; Gordon H Williams; Benjamin D Levine Journal: Hypertension Date: 2011-06-20 Impact factor: 10.190
Authors: Kanika Bagai; Yanna Song; John F Ling; Beth Malow; Bonnie K Black; Italo Biaggioni; David Robertson; Satish R Raj Journal: J Clin Sleep Med Date: 2011-04-15 Impact factor: 4.062
Authors: Miroslava Macova; Ines Armando; Jin Zhou; Gustavo Baiardi; Dmitri Tyurmin; Ignacio M Larrayoz-Roldan; Juan M Saavedra Journal: Neuroendocrinology Date: 2008-08-04 Impact factor: 4.914
Authors: Prasuna Muppa; Robert S Sheldon; Maureen McRae; Nancy R Keller; Deborah Ritchie; Andrew D Krahn; Carlos A Morillo; Teresa Kus; Mario Talajic; Satish R Raj Journal: Clin Auton Res Date: 2013-03-07 Impact factor: 4.435
Authors: Jessica A Eccles; Andrew P Owens; Christopher J Mathias; Satoshi Umeda; Hugo D Critchley Journal: Front Neurosci Date: 2015-02-10 Impact factor: 4.677
Authors: William T Gunning; Heather Kvale; Paula M Kramer; Beverly L Karabin; Blair P Grubb Journal: J Am Heart Assoc Date: 2019-09-09 Impact factor: 5.501
Authors: William T Gunning; Stanislaw M Stepkowski; Paula M Kramer; Beverly L Karabin; Blair P Grubb Journal: J Clin Med Date: 2021-02-06 Impact factor: 4.241
Authors: Karen C Peebles; Isabella Tan; Mark Butlin; Felicity Collins; Louise Tofts; Alberto P Avolio; Verity Pacey Journal: Am J Med Genet A Date: 2022-02-27 Impact factor: 2.578