| Literature DB >> 22718943 |
J Veenemans1, J W Mouton, J A J W Kluytmans, R Donnely, C Verhulst, P H J van Keulen.
Abstract
We assessed the effect of increasing manganese concentrations in test media (0.001 to 1,024 mg/liter) on MICs of tigecycline. For both broth microdilution (BMD) and Etests, this effect was negligible for physiological concentrations, but MICs increased when concentrations exceeded 8 mg/liter. Susceptibility testing should be performed on media with standardized low manganese content.Entities:
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Year: 2012 PMID: 22718943 PMCID: PMC3421825 DOI: 10.1128/JCM.01485-12
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948