Kenneth Kok1, Ian McCafferty, Andrew Monaghan, Hiroshi Nishikawa. 1. Department of Plastic and Reconstructive Surgery, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, West Midlands, United Kingdom. kennethkok@gmail.com
Abstract
INTRODUCTION AND AIMS: Sclerotherapy has become first line treatment for most venous malformations and some lymphatic malformations. We aimed to measure our sclerotherapy treatment success using 3% sodium tetradecyl sulphate (STD) and describe our experience. MATERIALS AND METHODS: Retrospective five year review (Jan 04-09) of children with vascular malformations treated at our centre with 3% STD. Patients were classified using the Birmingham classification and treatment success was measured through case note review and pre- and post-treatment photographs. FINDINGS AND RESULTS: Forty-three (84.3%) of the 51 patients with vascular malformations (VM) who underwent sclerotherapy derived a benefit. Twelve patients (23.5%) had an excellent result, 31 (60.8%) were improved whilst eight (15.7%) were unchanged. Using Fisher's exact test, there was a statistically significant difference in achieving complete resolution of superficial VMs compared to lesions involving the deeper layers of the head and neck. 17.6% of patients developed a complication with an overall complication rate of 12.2% per injection. There was one major complication with the remainder consisting of superficial skin necrosis that resolved conservatively. CONCLUSIONS: Treatment with 3% STD sclerotherapy is effective in venous and some lymphatic vascular malformations. It should be considered an important treatment modality within a multi-disciplinary setting in these difficult problems.
INTRODUCTION AND AIMS: Sclerotherapy has become first line treatment for most venous malformations and some lymphatic malformations. We aimed to measure our sclerotherapy treatment success using 3% sodium tetradecyl sulphate (STD) and describe our experience. MATERIALS AND METHODS: Retrospective five year review (Jan 04-09) of children with vascular malformations treated at our centre with 3% STD. Patients were classified using the Birmingham classification and treatment success was measured through case note review and pre- and post-treatment photographs. FINDINGS AND RESULTS: Forty-three (84.3%) of the 51 patients with vascular malformations (VM) who underwent sclerotherapy derived a benefit. Twelve patients (23.5%) had an excellent result, 31 (60.8%) were improved whilst eight (15.7%) were unchanged. Using Fisher's exact test, there was a statistically significant difference in achieving complete resolution of superficial VMs compared to lesions involving the deeper layers of the head and neck. 17.6% of patients developed a complication with an overall complication rate of 12.2% per injection. There was one major complication with the remainder consisting of superficial skin necrosis that resolved conservatively. CONCLUSIONS: Treatment with 3% STD sclerotherapy is effective in venous and some lymphatic vascular malformations. It should be considered an important treatment modality within a multi-disciplinary setting in these difficult problems.
Authors: Charlotte L Oliver; Judy Brown; Mike Watkins; Ian McCafferty; Richard J Oliver Journal: Cardiovasc Intervent Radiol Date: 2021-03-11 Impact factor: 2.740
Authors: Eeva Castrén; Johanna Aronniemi; Tuomas Klockars; Johanna Pekkola; Kimmo Lappalainen; Pia Vuola; Päivi Salminen; Anne Pitkäranta Journal: Eur Arch Otorhinolaryngol Date: 2015-03-04 Impact factor: 2.503