Literature DB >> 22717621

Iminosugar-ferrocene conjugates as potential anticancer agents.

Audrey Hottin1, Faustine Dubar, Agata Steenackers, Philippe Delannoy, Christophe Biot, Jean-Bernard Behr.   

Abstract

We prepared a series of new iminosugar-ferrocene hybrids displaying potent inhibition of fucosidase (bovine kidney) and inactivation of MDA-MB-231 breast cancer cells proliferation at low micromolar concentrations. The synthetic route brought to light an unprecedented isomerisation of a 2-ethanalylpyrrolidine.

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Year:  2012        PMID： 22717621     DOI： 10.1039/c2ob25727k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  6 in total

Review 1.  An overview on the synthesis of carbohydrate-based molecules with biological activity related to neurodegenerative diseases.

Authors:  João Paulo B Lopes; Luana Silva; Diogo S Lüdtke
Journal:  RSC Med Chem       Date:  2021-09-08

2.  Identification of Novel Human Breast Carcinoma (MDA-MB-231) Cell Growth Modulators from a Carbohydrate-Based Diversity Oriented Synthesis Library.

Authors:  Elena Lenci; Riccardo Innocenti; Alessio Biagioni; Gloria Menchi; Francesca Bianchini; Andrea Trabocchi
Journal:  Molecules       Date:  2016-10-20       Impact factor: 4.411

Review 3.  Ferrocene-Based Compounds with Antimalaria/Anticancer Activity.

Authors:  Sijongesonke Peter; Blessing Atim Aderibigbe
Journal:  Molecules       Date:  2019-10-07       Impact factor: 4.411

4.  Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors.

Authors:  Ana I Ahuja-Casarín; Penélope Merino-Montiel; José Luis Vega-Baez; Sara Montiel-Smith; Miguel X Fernandes; Irene Lagunes; Inés Maya; José M Padrón; Óscar López; José G Fernández-Bolaños
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051

Review 5.  Multivalent Pyrrolidine Iminosugars: Synthesis and Biological Relevance.

Authors:  Yali Wang; Jian Xiao; Aiguo Meng; Chunyan Liu
Journal:  Molecules       Date:  2022-08-24       Impact factor: 4.927

Review 6.  Glycoside Mimics from Glycosylamines: Recent Progress.

Authors:  Cyril Nicolas; Olivier R Martin
Journal:  Molecules       Date:  2018-07-02       Impact factor: 4.411
  6 in total

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