Literature DB >> 22716984

Effect of a monoclonal antibody to PCSK9 on LDL cholesterol.

Yajnavalka Banerjee, Karna Shah, Khalid Al-Rasadi.   

Abstract

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Year:  2012        PMID： 22716984     DOI： 10.1056/NEJMc1204929

Source DB:  PubMed          Journal:  N Engl J Med        ISSN： 0028-4793            Impact factor:   91.245


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  2 in total

1.  Mutation in the PCSK9 Gene in Omani Arab Subjects with Autosomal Dominant Hypercholesterolemia and its Effect on PCSK9 Protein Structure.

Authors:  Khalid Al-Waili; Ward Al-Muna Al-Zidi; Abdul Rahim Al-Abri; Khalid Al-Rasadi; Hilal Ali Al-Sabti; Karna Shah; Abdullah Al-Futaisi; Ibrahim Al-Zakwani; Yajnavalka Banerjee
Journal:  Oman Med J       Date:  2013-01

2.  Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial.

Authors:  Kevin Fitzgerald; Maria Frank-Kamenetsky; Svetlana Shulga-Morskaya; Abigail Liebow; Brian R Bettencourt; Jessica E Sutherland; Renta M Hutabarat; Valerie A Clausen; Verena Karsten; Jeffrey Cehelsky; Saraswathy V Nochur; Victor Kotelianski; Jay Horton; Timothy Mant; Joseph Chiesa; James Ritter; Malathy Munisamy; Akshay K Vaishnaw; Jared A Gollob; Amy Simon
Journal:  Lancet       Date:  2013-10-03       Impact factor: 79.321
  2 in total

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