Literature DB >> 22715187

Necrotising granulomatous lymphadenitis.

François Alves1, Ana Baptista, Helena Brito, Idálio Mendonça.   

Abstract

Extrapulmonary tuberculosis (EPTB) is defined as Mycobacterium TB through Ziehl-Neelsen acid-fast stain and culture in Loewenstein-Jensen in a tissue from a site other than lung parenchyma, in association with clinical or imaging findings compatible with infection locally. The authors report a case of a patient who presented with asthenia, anorexia and weight loss. He complained of fever, chills and night sweats of 1-week duration. The thoracic scan reveals lymph node enlargement in the left axilla and pleural effusion and the histological study revealed a necrotising granulomatous lymphadenitis. It was decided to initiate antituberculous drugs with a good response. EPTB is a difficult diagnostic because lymph nodes contain few tubercle bacilli, leading to a low sensitivity of smear microscopy detection. The introduction of antituberculous agents is the cornerstone of management of such infections and, occasionally, it is the only way to make a diagnosis.

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Year:  2011        PMID: 22715187      PMCID: PMC3062882          DOI: 10.1136/bcr.11.2010.3548

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  22 in total

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2.  Diagnosis of extrapulmonary tuberculosis by smear, culture, and PCR using universal sample processing technology.

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Journal:  Eur J Intern Med       Date:  2000-06       Impact factor: 4.487

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Authors:  B C Jha; A Dass; N M Nagarkar; R Gupta; S Singhal
Journal:  Postgrad Med J       Date:  2001-03       Impact factor: 2.401

Review 6.  Epidemiology of HIV-TB in Asia.

Authors:  Jai P Narain; Ying-Ru Lo
Journal:  Indian J Med Res       Date:  2004-10       Impact factor: 2.375

7.  Treatment of lymph node tuberculosis--a randomized clinical trial of two 6-month regimens.

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Journal:  Trop Med Int Health       Date:  2005-11       Impact factor: 2.622

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Journal:  Medicine (Baltimore)       Date:  1991-11       Impact factor: 1.889

9.  The epidemiology of tuberculosis in San Francisco. A population-based study using conventional and molecular methods.

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Journal:  N Engl J Med       Date:  1994-06-16       Impact factor: 91.245

10.  Identification of risk factors for extrapulmonary tuberculosis.

Authors:  Zhenhua Yang; Ying Kong; Frank Wilson; Betsy Foxman; Annadell H Fowler; Carl F Marrs; M Donald Cave; Joseph H Bates
Journal:  Clin Infect Dis       Date:  2003-12-19       Impact factor: 9.079

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  1 in total

1.  Woman with necrotising granulomatous lymphadenitis: the key was in anamnesis and physical examination.

Authors:  D Sánchez Fabra; F Abad Villamor; S Clemos Matamoros; J Valle Puey; M J Igúzquiza Pellejero; A L García Forcada
Journal:  Rev Esp Quimioter       Date:  2022-02-02       Impact factor: 1.553

  1 in total

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