Literature DB >> 22714783

Hemorrhoid management in patients with radiation proctitis.

Melinda Hawkins1, Richard Billingham, Amir Bastawrous.   

Abstract

PURPOSE: Management of rectal bleeding in patients with radiation proctitis presents a conundrum for practitioners. Surgeons are appropriately concerned about using conventional methods of treatment in these patients, such as cautery for bleeding areas in the rectum, rubber band ligation, or excision of internal and/or external hemorrhoids, for fear of poor healing and possible exacerbation of the original problem. Few randomized controlled trials are available on the treatment of radiation proctitis alone, and no literature exists pertaining to the management of symptomatic hemorrhoids in the radiated patient.
METHODS: In the absence of observational studies, the authors created an email survey to distribute to the membership of the American Society of Colon and Rectal Surgeons in order to try to identify current management practices for radiation proctitis and for the treatment of their symptomatic hemorrhoids.
RESULTS: Of the 327 respondents, 85 % favored the use of topical formalin to treat radiation proctitis, while 42 % additionally used argon plasma coagulation. Only 25 % of practitioners report using sucralfate, though existing data on this therapy are promising. Regarding the management of hemorrhoids in patients with a history of rectal irradiation, 55 % of respondents hoped treatment of radiation proctitis alone would solve the problem. Forty-three percent reported using rubber band ligation, 30 % using hemorrhoidectomy, and 18 % using sclerotherapy.
CONCLUSIONS: While most respondents treated radiation proctitis alone in patients with symptomatic hemorrhoids, many also felt rubber band ligation, hemorrhoidectomy, and sclerotherapy are safe and effective alternative therapies in this population.

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Year:  2012        PMID: 22714783     DOI: 10.1007/s00384-012-1512-9

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  11 in total

Review 1.  Chronic radiation proctitis.

Authors:  P P Tagkalidis; J J Tjandra
Journal:  ANZ J Surg       Date:  2001-04       Impact factor: 1.872

2.  Radiation-induced proctosigmoiditis. Prospective, randomized, double-blind controlled trial of oral sulfasalazine plus rectal steroids versus rectal sucralfate.

Authors:  R Kochhar; F Patel; A Dhar; S C Sharma; S Ayyagari; R Aggarwal; M K Goenka; B D Gupta; S K Mehta
Journal:  Dig Dis Sci       Date:  1991-01       Impact factor: 3.199

3.  Efficacy and complications of argon plasma coagulation for hematochezia related to radiation proctopathy.

Authors:  Raphael T Villavicencio; Douglas K Rex; Emad Rahmani
Journal:  Gastrointest Endosc       Date:  2002-01       Impact factor: 9.427

4.  A randomized prospective study of endoscopic bipolar electrocoagulation and heater probe treatment of chronic rectal bleeding from radiation telangiectasia.

Authors:  D M Jensen; G A Machicado; S Cheng; M E Jensen; R Jutabha
Journal:  Gastrointest Endosc       Date:  1997-01       Impact factor: 9.427

5.  Natural history of late radiation proctosigmoiditis treated with topical sucralfate suspension.

Authors:  R Kochhar; P V Sriram; S C Sharma; R C Goel; F Patel
Journal:  Dig Dis Sci       Date:  1999-05       Impact factor: 3.199

6.  Short chain fatty acids are effective in short-term treatment of chronic radiation proctitis: randomized, double-blind, controlled trial.

Authors:  A Pinto; P Fidalgo; M Cravo; J Midões; P Chaves; J Rosa; M dos Anjos Brito; C N Leitão
Journal:  Dis Colon Rectum       Date:  1999-06       Impact factor: 4.585

7.  A prospective, randomized, double-blind, placebo-controlled trial of retinol palmitate (vitamin A) for symptomatic chronic radiation proctopathy.

Authors:  Eli D Ehrenpreis; Ashesh Jani; Josh Levitsky; Joseph Ahn; John Hong
Journal:  Dis Colon Rectum       Date:  2005-01       Impact factor: 4.585

8.  Hyperbaric oxygen treatment of chronic refractory radiation proctitis: a randomized and controlled double-blind crossover trial with long-term follow-up.

Authors:  Richard E Clarke; L M Catalina Tenorio; James R Hussey; Akin S Toklu; D Lindsie Cone; Jose G Hinojosa; Samir P Desai; Luis Dominguez Parra; Sylvia D Rodrigues; Robert J Long; Margaret B Walker
Journal:  Int J Radiat Oncol Biol Phys       Date:  2008-03-14       Impact factor: 7.038

9.  Formalin treatment of radiation-induced hemorrhagic proctitis.

Authors:  E Rubinstein; T Ibsen; R B Rasmussen; E Reimer; B L Sørensen
Journal:  Am J Gastroenterol       Date:  1986-01       Impact factor: 10.864

10.  Two percent formalin retention enemas for hemorrhagic radiation proctitis: a preliminary report.

Authors:  Ramaiyer Raghu Raman
Journal:  Dis Colon Rectum       Date:  2007-07       Impact factor: 4.585

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  1 in total

Review 1.  Chronic radiation proctopathy: A practical review of endoscopic treatment.

Authors:  Luciano Lenz; Rachel Rohr; Frank Nakao; Ermelindo Libera; Angelo Ferrari
Journal:  World J Gastrointest Surg       Date:  2016-02-27
  1 in total

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