OBJECTIVES: The frequency of diagnosis of bipolar disorder has risen dramatically in children and adolescents. The DSM-V Work Group has suggested a new diagnosis termed disruptive mood dysregulation disorder (DMDD) (formerly temper dysregulation disorder with dysphoria) to reduce the rate of false diagnosis of bipolar disorder in young people. We sought to determine if the application of the proposed diagnostic criteria for DMDD would reduce the rate of diagnosis of bipolar disorder in children. PATIENTS AND METHODS: Eighty-two consecutively hospitalized children, ages 5 to 12 years, on a children's inpatient unit were rigorously diagnosed using admission interviews of the parents and the child, rating scales, and observation over the course of hospitalization. RESULTS: Overall, 30.5% of inpatient children met criteria for DMDD by parent report, and 15.9% by inpatient unit observation. Fifty-six percent of inpatient children had parent-reported manic symptoms. Of those, 45.7% met criteria for DMDD by parent-report, though only 17.4% did when observed on the inpatient unit. CONCLUSION: Although DMDD does decrease the rate of diagnosis of bipolar disorder in children, how much depends on whether history or observation is used.
OBJECTIVES: The frequency of diagnosis of bipolar disorder has risen dramatically in children and adolescents. The DSM-V Work Group has suggested a new diagnosis termed disruptive mood dysregulation disorder (DMDD) (formerly temper dysregulation disorder with dysphoria) to reduce the rate of false diagnosis of bipolar disorder in young people. We sought to determine if the application of the proposed diagnostic criteria for DMDD would reduce the rate of diagnosis of bipolar disorder in children. PATIENTS AND METHODS: Eighty-two consecutively hospitalized children, ages 5 to 12 years, on a children's inpatient unit were rigorously diagnosed using admission interviews of the parents and the child, rating scales, and observation over the course of hospitalization. RESULTS: Overall, 30.5% of inpatient children met criteria for DMDD by parent report, and 15.9% by inpatient unit observation. Fifty-six percent of inpatient children had parent-reported manic symptoms. Of those, 45.7% met criteria for DMDD by parent-report, though only 17.4% did when observed on the inpatient unit. CONCLUSION: Although DMDD does decrease the rate of diagnosis of bipolar disorder in children, how much depends on whether history or observation is used.
Authors: Simone P Haller; Katharina Kircanski; Argyris Stringaris; Michal Clayton; Hong Bui; Courtney Agorsor; Sofia I Cardenas; Kenneth E Towbin; Daniel S Pine; Ellen Leibenluft; Melissa A Brotman Journal: Behav Ther Date: 2019-11-27
Authors: L R Dougherty; V C Smith; S J Bufferd; G A Carlson; A Stringaris; E Leibenluft; D N Klein Journal: Psychol Med Date: 2014-01-21 Impact factor: 7.723
Authors: Michael B First; Wolfgang Gaebel; Mario Maj; Dan J Stein; Cary S Kogan; John B Saunders; Vladimir B Poznyak; Oye Gureje; Roberto Lewis-Fernández; Andreas Maercker; Chris R Brewin; Marylene Cloitre; Angelica Claudino; Kathleen M Pike; Gillian Baird; David Skuse; Richard B Krueger; Peer Briken; Jeffrey D Burke; John E Lochman; Spencer C Evans; Douglas W Woods; Geoffrey M Reed Journal: World Psychiatry Date: 2021-02 Impact factor: 49.548
Authors: Carrie A H Vaudreuil; Stephen V Faraone; Maura Di Salvo; Janet R Wozniak; Rebecca A Wolenski; Nicholas W Carrellas; Joseph Biederman Journal: Bipolar Disord Date: 2018-12-19 Impact factor: 6.744
Authors: Andrew J Freeman; Eric A Youngstrom; Jennifer K Youngstrom; Robert L Findling Journal: J Child Adolesc Psychopharmacol Date: 2016-01-08 Impact factor: 2.576