Literature DB >> 22712841

Integrin triplets of marine sponges in human D2 receptor heteromers.

Alexander O Tarakanov1, Kjell G Fuxe, Dasiel O Borroto-Escuela.   

Abstract

The evidence for the existence of receptor heteromers opens up a new field for a better understanding of neural transmission. Based on our theory, we have discovered main triplets of amino acid residues in cell-adhesion receptors of marine sponges, which appear also as homologies in several dopamine D2 receptor heteromers of human brain. The obtained results probably mean a general molecular mechanism for receptor-receptor interactions in heteromers originated from the lowest animals (marine sponges).

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22712841     DOI： 10.3109/10799893.2012.692119

Source DB:  PubMed          Journal:  J Recept Signal Transduct Res        ISSN： 1079-9893            Impact factor:   2.092


  6 in total

Review 1.  Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field.

Authors:  Kjell Fuxe; Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Miklós Palkovits; Alexander O Tarakanov; Francisco Ciruela; Luigi F Agnati
Journal:  Neuropsychopharmacology       Date:  2013-09-06       Impact factor: 7.853

2.  On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation.

Authors:  Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Alicia Rivera; Kathleen Van Craenenbroeck; Alexander O Tarakanov; Luigi F Agnati; Kjell Fuxe
Journal:  Evid Based Complement Alternat Med       Date:  2013-07-17       Impact factor: 2.629

3.  IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia.

Authors:  Dasiel O Borroto-Escuela; Alexander O Tarakanov; Karl Bechter; Kjell Fuxe
Journal:  Front Psychiatry       Date:  2017-02-15       Impact factor: 4.157

4.  Integrin triplets of marine sponges in the murine and human MHCI-CD8 interface and in the interface of human neural receptor heteromers and subunits.

Authors:  Alexander O Tarakanov; Kjell G Fuxe
Journal:  Springerplus       Date:  2013-03-22

5.  On the existence and function of galanin receptor heteromers in the central nervous system.

Authors:  Kjell Fuxe; Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Alexander O Tarakanov; Feliciano Calvo; Pere Garriga; Mercé Tena; Manuel Narvaez; Carmelo Millón; Concepción Parrado; Francisco Ciruela; Luigi F Agnati; José A Narvaez; Zaida Díaz-Cabiale
Journal:  Front Endocrinol (Lausanne)       Date:  2012-10-26       Impact factor: 5.555

6.  The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components.

Authors:  Dasiel O Borroto-Escuela; Ismel Brito; Wilber Romero-Fernandez; Michael Di Palma; Julia Oflijan; Kamila Skieterska; Jolien Duchou; Kathleen Van Craenenbroeck; Diana Suárez-Boomgaard; Alicia Rivera; Diego Guidolin; Luigi F Agnati; Kjell Fuxe
Journal:  Int J Mol Sci       Date:  2014-05-14       Impact factor: 5.923
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.