Literature DB >> 22712563

Lessons from natural products chemistry can offer novel approaches for synthetic chemistry in drug discovery.

Natalya I Vasilevich1, Roman V Kombarov, Dmitry V Genis, Michael A Kirpichenok.   

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Year:  2012        PMID: 22712563     DOI: 10.1021/jm300344v

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  8 in total

1.  Design and synthesis of novel arctigenin analogues for the amelioration of metabolic disorders.

Authors:  Shudong Duan; Suling Huang; Jian Gong; Yu Shen; Limin Zeng; Ying Feng; Wenming Ren; Ying Leng; Youhong Hu
Journal:  ACS Med Chem Lett       Date:  2015-03-05       Impact factor: 4.345

2.  Xiao-Ai-Ping, a TCM Injection, Enhances the Antigrowth Effects of Cisplatin on Lewis Lung Cancer Cells through Promoting the Infiltration and Function of CD8(+) T Lymphocytes.

Authors:  Wanshuai Li; Yang Yang; Zijun Ouyang; Qi Zhang; Lu Wang; Feifei Tao; Yongqian Shu; Yanhong Gu; Qiang Xu; Yang Sun
Journal:  Evid Based Complement Alternat Med       Date:  2013-07-17       Impact factor: 2.629

3.  Spirocyclic chromanes exhibit antiplasmodial activities and inhibit all intraerythrocytic life cycle stages.

Authors:  Bracken F Roberts; Iredia D Iyamu; Sukjun Lee; Eunyoung Lee; Lawrence Ayong; Dennis E Kyle; Yu Yuan; Roman Manetsch; Debopam Chakrabarti
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2016-02-12       Impact factor: 4.077

4.  4-Nitro styrylquinoline is an antimalarial inhibiting multiple stages of Plasmodium falciparum asexual life cycle.

Authors:  Bracken F Roberts; Yongsheng Zheng; Jacob Cleaveleand; Sukjun Lee; Eunyoung Lee; Lawrence Ayong; Yu Yuan; Debopam Chakrabarti
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2017-02-21       Impact factor: 4.077

Review 5.  Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis.

Authors:  Bernardo Pereira Moreira; Michael H W Weber; Simone Haeberlein; Annika S Mokosch; Bernhard Spengler; Christoph G Grevelding; Franco H Falcone
Journal:  Molecules       Date:  2022-02-19       Impact factor: 4.411

6.  Prioritization of anti-malarial hits from nature: chemo-informatic profiling of natural products with in vitro antiplasmodial activities and currently registered anti-malarial drugs.

Authors:  Samuel Ayodele Egieyeh; James Syce; Sarel F Malan; Alan Christoffels
Journal:  Malar J       Date:  2016-01-29       Impact factor: 2.979

7.  Investigations to the Antibacterial Mechanism of Action of Kendomycin.

Authors:  Yasser A Elnakady; Indranil Chatterjee; Markus Bischoff; Manfred Rohde; Michaele Josten; Hans-Georg Sahl; Mathias Herrmann; Rolf Müller
Journal:  PLoS One       Date:  2016-01-21       Impact factor: 3.240

8.  Kaempferol mitigates Endoplasmic Reticulum Stress Induced Cell Death by targeting caspase 3/7.

Authors:  Ahmad Abdullah; Palaniyandi Ravanan
Journal:  Sci Rep       Date:  2018-02-01       Impact factor: 4.379

  8 in total

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