BACKGROUND: This study investigated impaired self-awareness of motor deficits in nondemented, nondepressed Parkinson's disease (PD) patients during a defined clinical on state. METHODS: Twenty-eight PD patients were examined. Patients' self-ratings and experts' ratings of patients' motor performance were compared. Patient-examiner discrepancies and level of impairment determined severity of impaired self-awareness. Motor exam assessed overall motor functioning, hemibody impairment, and 4 motor phenotypes. Neuropsychological tests were also conducted. RESULTS: Signs of impaired self-awareness were present in 17 patients (60.7%). Higher severity of impaired self-awareness correlated significantly with higher postural-instability and gait-difficulty off scores (r = .575; P = .001), overall motor off scores (r = .569; P = .002), and higher left hemibody off scores (r = .490; P = .008). In multiple linear regression analyses, higher postural-instability and gait-difficulty off scores remained as the only significant predictor of impaired self-awareness severity. CONCLUSIONS: Postural instability and gait difficulties, disease severity, and right hemisphere dysfunction seem to contribute to impaired self-awareness.
BACKGROUND: This study investigated impaired self-awareness of motor deficits in nondemented, nondepressed Parkinson's disease (PD) patients during a defined clinical on state. METHODS: Twenty-eight PDpatients were examined. Patients' self-ratings and experts' ratings of patients' motor performance were compared. Patient-examiner discrepancies and level of impairment determined severity of impaired self-awareness. Motor exam assessed overall motor functioning, hemibody impairment, and 4 motor phenotypes. Neuropsychological tests were also conducted. RESULTS: Signs of impaired self-awareness were present in 17 patients (60.7%). Higher severity of impaired self-awareness correlated significantly with higher postural-instability and gait-difficulty off scores (r = .575; P = .001), overall motor off scores (r = .569; P = .002), and higher left hemibody off scores (r = .490; P = .008). In multiple linear regression analyses, higher postural-instability and gait-difficulty off scores remained as the only significant predictor of impaired self-awareness severity. CONCLUSIONS: Postural instability and gait difficulties, disease severity, and right hemisphere dysfunction seem to contribute to impaired self-awareness.
Authors: Matthias Löhle; Alexander Bremer; Florin Gandor; Jonathan Timpka; Per Odin; Georg Ebersbach; Alexander Storch Journal: NPJ Parkinsons Dis Date: 2022-06-02
Authors: Sara Palermo; Leonardo Lopiano; Rosalba Morese; Maurizio Zibetti; Alberto Romagnolo; Mario Stanziano; Mario Giorgio Rizzone; Giuliano Carlo Geminiani; Maria Consuelo Valentini; Martina Amanzio Journal: Front Psychol Date: 2018-09-20
Authors: Megan Rose Readman; Neil M McLatchie; Ellen Poliakoff; Trevor J Crawford; Sally A Linkenauger Journal: Atten Percept Psychophys Date: 2021-07-06 Impact factor: 2.199