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Literature DB >> 22710630

Alzheimer disease: Insulin resistance and AD--extending the translational path.

Suzanne Craft.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2012 PMID： 22710630 DOI： 10.1038/nrneurol.2012.112

Source DB: PubMed Journal: Nat Rev Neurol ISSN： 1759-4758 Impact factor: 42.937

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9 in total

1. Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial.

Authors: Suzanne Craft; Laura D Baker; Thomas J Montine; Satoshi Minoshima; G Stennis Watson; Amy Claxton; Matthew Arbuckle; Maureen Callaghan; Elaine Tsai; Stephen R Plymate; Pattie S Green; James Leverenz; Donna Cross; Brooke Gerton
Journal: Arch Neurol Date: 2011-09-12

2. Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.

Authors: Lixia Zhao; Bruce Teter; Takashi Morihara; Giselle P Lim; Surendra S Ambegaokar; Oliver J Ubeda; Sally A Frautschy; Greg M Cole
Journal: J Neurosci Date: 2004-12-08 Impact factor: 6.167

3. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.

Authors: Konrad Talbot; Hoau-Yan Wang; Hala Kazi; Li-Ying Han; Kalindi P Bakshi; Andres Stucky; Robert L Fuino; Krista R Kawaguchi; Andrew J Samoyedny; Robert S Wilson; Zoe Arvanitakis; Julie A Schneider; Bryan A Wolf; David A Bennett; John Q Trojanowski; Steven E Arnold
Journal: J Clin Invest Date: 2012-04 Impact factor: 14.808

4. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.

Authors: Theresa R Bomfim; Leticia Forny-Germano; Luciana B Sathler; Jordano Brito-Moreira; Jean-Christophe Houzel; Helena Decker; Michael A Silverman; Hala Kazi; Helen M Melo; Paula L McClean; Christian Holscher; Steven E Arnold; Konrad Talbot; William L Klein; Douglas P Munoz; Sergio T Ferreira; Fernanda G De Felice
Journal: J Clin Invest Date: 2012-04 Impact factor: 14.808

Review 5. The effect of glucagon-like peptide 1 on cardiovascular risk.

Authors: Jacob Sivertsen; Jaya Rosenmeier; Jens J Holst; Tina Vilsbøll
Journal: Nat Rev Cardiol Date: 2012-01-31 Impact factor: 32.419

6. Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.

Authors: Qiu-Lan Ma; Fusheng Yang; Emily R Rosario; Oliver J Ubeda; Walter Beech; Dana J Gant; Ping Ping Chen; Beverly Hudspeth; Cory Chen; Yongle Zhao; Harry V Vinters; Sally A Frautschy; Greg M Cole
Journal: J Neurosci Date: 2009-07-15 Impact factor: 6.167

7. Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type.

Authors: S Hoyer; R Nitsch
Journal: J Neural Transm Date: 1989 Impact factor: 3.575

8. Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease.

Authors: Dongfeng Cao; Hailin Lu; Terry L Lewis; Ling Li
Journal: J Biol Chem Date: 2007-10-17 Impact factor: 5.157

9. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.

Authors: Lap Ho; Weiping Qin; Patrick N Pompl; Zhongmin Xiang; Jun Wang; Zhong Zhao; Yuanzhen Peng; Gina Cambareri; Anne Rocher; Charles V Mobbs; Patrick R Hof; Giulio Maria Pasinetti
Journal: FASEB J Date: 2004-03-19 Impact factor: 5.191

9 in total

46 in total

1. Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo.

Authors: Shannon L Macauley; Molly Stanley; Emily E Caesar; Steven A Yamada; Marcus E Raichle; Ronaldo Perez; Thomas E Mahan; Courtney L Sutphen; David M Holtzman
Journal: J Clin Invest Date: 2015-05-04 Impact factor: 14.808

2. Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer's Disease.

Authors: Miren Ettcheto; Elena Sánchez-López; Yaiza Gómez-Mínguez; Henrry Cabrera; Oriol Busquets; Carlos Beas-Zarate; Maria Luisa García; Eva Carro; Gemma Casadesus; Carme Auladell; Manuel Vázquez Carrera; Jaume Folch; Antoni Camins
Journal: Mol Neurobiol Date: 2018-02-05 Impact factor: 5.590

10. Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.

Authors: Dema Najem; Michelle Bamji-Mirza; Ze Yang; Wandong Zhang
Journal: Neurosci Bull Date: 2016-05-20 Impact factor: 5.203

Alzheimer disease: Insulin resistance and AD--extending the translational path.

1. Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial.

2. Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.

3. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.

4. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.

Review 5. The effect of glucagon-like peptide 1 on cardiovascular risk.

6. Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.

7. Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type.

8. Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease.

9. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.

1. Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo.

2. Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer's Disease.

3. Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease.

Review 4. Insulin resistance in Alzheimer's disease.

5. Blood glucose, diet-based glycemic load and cognitive aging among dementia-free older adults.

6. Dietary Factors and Cognitive Decline.

Review 7. Impaired insulin action in the human brain: causes and metabolic consequences.

Review 8. Evaluating the Role of Hormone Therapy in Postmenopausal Women with Alzheimer's Disease.

Review 9. Alzheimer's disease and insulin resistance: translating basic science into clinical applications.

10. Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.