BACKGROUND: The highest risk for stroke is among survivors of strokes or transient ischemic attacks (TIA). However, use of proven-effective cardiovascular medications to control stroke risk is suboptimal, particularly among the Black and Latino populations disproportionately impacted by stroke. METHODS: A partnership of Harlem and Bronx community representatives, stroke survivors, researchers, clinicians, outreach workers and patient educators used community-based participatory research to conceive and develop the Prevent Recurrence of All Inner-city Strokes through Education (PRAISE) trial. Using data from focus groups with stroke survivors, they tailored a peer-led, community-based chronic disease self-management program to address stroke risk factors. PRAISE will test, in a randomized controlled trial, whether this stroke education intervention improves blood pressure control and a composite outcome of blood pressure control, lipid control, and use of antithrombotic medications. RESULTS: Of the 582 survivors of stroke and TIA enrolled thus far, 81% are Black or Latino and 56% have an annual income less than $15,000. Many (33%) do not have blood pressures in the target range, and most (66%) do not have control of all three major stroke risk factors. CONCLUSIONS: Rates of stroke recurrence risk factors remain suboptimal in the high risk, urban, predominantly minority communities studied. With a community-partnered approach, PRAISE has recruited a large number of stroke and TIA survivors to date, and may prove successful in engaging those at highest risk for stroke and reducing disparities in stroke outcomes in inner-city communities.
RCT Entities:
BACKGROUND: The highest risk for stroke is among survivors of strokes or transient ischemic attacks (TIA). However, use of proven-effective cardiovascular medications to control stroke risk is suboptimal, particularly among the Black and Latino populations disproportionately impacted by stroke. METHODS: A partnership of Harlem and Bronx community representatives, stroke survivors, researchers, clinicians, outreach workers and patient educators used community-based participatory research to conceive and develop the Prevent Recurrence of All Inner-city Strokes through Education (PRAISE) trial. Using data from focus groups with stroke survivors, they tailored a peer-led, community-based chronic disease self-management program to address stroke risk factors. PRAISE will test, in a randomized controlled trial, whether this stroke education intervention improves blood pressure control and a composite outcome of blood pressure control, lipid control, and use of antithrombotic medications. RESULTS: Of the 582 survivors of stroke and TIA enrolled thus far, 81% are Black or Latino and 56% have an annual income less than $15,000. Many (33%) do not have blood pressures in the target range, and most (66%) do not have control of all three major stroke risk factors. CONCLUSIONS: Rates of stroke recurrence risk factors remain suboptimal in the high risk, urban, predominantly minority communities studied. With a community-partnered approach, PRAISE has recruited a large number of stroke and TIA survivors to date, and may prove successful in engaging those at highest risk for stroke and reducing disparities in stroke outcomes in inner-city communities.
Authors: Alan E Hubbard; Jennifer Ahern; Nancy L Fleischer; Mark Van der Laan; Sheri A Lippman; Nicholas Jewell; Tim Bruckner; William A Satariano Journal: Epidemiology Date: 2010-07 Impact factor: 4.822
Authors: C D Bushnell; D M Olson; X Zhao; W Pan; L O Zimmer; L B Goldstein; M J Alberts; S C Fagan; G C Fonarow; S C Johnston; C Kidwell; K A Labresh; B Ovbiagele; L Schwamm; E D Peterson Journal: Neurology Date: 2011-09-07 Impact factor: 9.910
Authors: Bruce Ovbiagele; Jeffrey L Saver; Andre Fredieu; Shuichi Suzuki; Scott Selco; Venkatakrishna Rajajee; Norma McNair; Tannaz Razinia; Chelsea S Kidwell Journal: Stroke Date: 2004-10-28 Impact factor: 7.914
Authors: Thomas G Pickering; John E Hall; Lawrence J Appel; Bonita E Falkner; John W Graves; Martha N Hill; Daniel H Jones; Theodore Kurtz; Sheldon G Sheps; Edward J Roccella Journal: J Clin Hypertens (Greenwich) Date: 2005-02 Impact factor: 3.738
Authors: Martha Sajatovic; Curtis Tatsuoka; Elisabeth Welter; Kari Colon-Zimmermann; Carol Blixen; Adam T Perzynski; Shelly Amato; Jamie Cage; Johnny Sams; Shirley M Moore; Svetlana Pundik; Sophia Sundararajan; Charles Modlin; Cathy Sila Journal: Am J Health Promot Date: 2017-03-06
Authors: Kezhen Fei; Emma K T Benn; Rennie Negron; Guedy Arniella; Stanley Tuhrim; Carol R Horowitz Journal: Stroke Date: 2015-12-01 Impact factor: 7.914
Authors: Rachel G Tabak; Kàimi A Sinclair; Ana A Baumann; Susan B Racette; Anne Sebert Kuhlmann; Michelle D Johnson-Jennings; Ross C Brownson Journal: Transl Behav Med Date: 2015-09-16 Impact factor: 3.046
Authors: C R Horowitz; N S Abul-Husn; S Ellis; M A Ramos; R Negron; M Suprun; R E Zinberg; T Sabin; D Hauser; N Calman; E Bagiella; E P Bottinger Journal: Contemp Clin Trials Date: 2015-12-30 Impact factor: 2.226
Authors: Ian M Kronish; Michael A Diefenbach; Donald E Edmondson; L Alison Phillips; Kezhen Fei; Carol R Horowitz Journal: J Gen Intern Med Date: 2013-01-04 Impact factor: 5.128