Literature DB >> 22710307

Peptide inhibitors: Four of a kind beats a pair.

Shawn B Bratton1.   

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Year:  2012        PMID： 22710307      PMCID： PMC3688271          DOI： 10.1038/nchembio.1000

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

1.  Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative.

Authors:  Andrew T N Tebbenkamp; Cameron Green; Guilian Xu; Eileen M Denovan-Wright; Aaron C Rising; Susan E Fromholt; Hilda H Brown; Debbie Swing; Ronald J Mandel; Lino Tessarollo; David R Borchelt
Journal:  Hum Mol Genet       Date:  2011-04-22       Impact factor: 6.150

Review 2.  The protein structures that shape caspase activity, specificity, activation and inhibition.

Authors:  Pablo Fuentes-Prior; Guy S Salvesen
Journal:  Biochem J       Date:  2004-12-01       Impact factor: 3.857

3.  Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation.

Authors:  Xiao-Jun Wang; Qin Cao; Xiang Liu; Kai-Tuo Wang; Wei Mi; Yan Zhang; Lan-Fen Li; Andrea C LeBlanc; Xiao-Dong Su
Journal:  EMBO Rep       Date:  2010-10-01       Impact factor: 8.807

4.  Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice.

Authors:  Valeria Uribe; Bibiana K Y Wong; Rona K Graham; Corey L Cusack; Niels H Skotte; Mahmoud A Pouladi; Yuanyun Xie; Konstantin Feinberg; Yimiao Ou; Yingbin Ouyang; Yu Deng; Sonia Franciosi; Nagat Bissada; Amanda Spreeuw; Weining Zhang; Dagmar E Ehrnhoefer; Kuljeet Vaid; Freda D Miller; Mohanish Deshmukh; David Howland; Michael R Hayden
Journal:  Hum Mol Genet       Date:  2012-01-18       Impact factor: 6.150

5.  Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.

Authors:  Rona K Graham; Yu Deng; Elizabeth J Slow; Brendan Haigh; Nagat Bissada; Ge Lu; Jacqueline Pearson; Jacqueline Shehadeh; Lisa Bertram; Zoe Murphy; Simon C Warby; Crystal N Doty; Sophie Roy; Cheryl L Wellington; Blair R Leavitt; Lynn A Raymond; Donald W Nicholson; Michael R Hayden
Journal:  Cell       Date:  2006-06-16       Impact factor: 41.582

6.  Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.

Authors:  Karen Stanger; Micah Steffek; Lijuan Zhou; Christine D Pozniak; Clifford Quan; Yvonne Franke; Jeff Tom; Christine Tam; Irina Krylova; J Michael Elliott; Joseph W Lewcock; Yingnan Zhang; Jeremy Murray; Rami N Hannoush
Journal:  Nat Chem Biol       Date:  2012-06-10       Impact factor: 15.040

7.  Discovery of an allosteric site in the caspases.

Authors:  Jeanne A Hardy; Joni Lam; Jack T Nguyen; Tom O'Brien; James A Wells
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205

8.  Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease.

Authors:  Huishan Guo; Steffen Albrecht; Martine Bourdeau; Tracy Petzke; Catherine Bergeron; Andrea C LeBlanc
Journal:  Am J Pathol       Date:  2004-08       Impact factor: 4.307

9.  The crystal structure of caspase-6, a selective effector of axonal degeneration.

Authors:  Renato Baumgartner; Gabriele Meder; Christophe Briand; Arnaud Decock; Allan D'arcy; Ulrich Hassiepen; Richard Morse; Martin Renatus
Journal:  Biochem J       Date:  2009-10-12       Impact factor: 3.857

10.  Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.

Authors:  E A Slee; M T Harte; R M Kluck; B B Wolf; C A Casiano; D D Newmeyer; H G Wang; J C Reed; D W Nicholson; E S Alnemri; D R Green; S J Martin
Journal:  J Cell Biol       Date:  1999-01-25       Impact factor: 10.539
  10 in total

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