Literature DB >> 22708765

Vitamin D and health in adults in Australia and New Zealand: a position statement.

Caryl A Nowson1, John J McGrath, Peter R Ebeling, Anjali Haikerwal, Robin M Daly, Kerrie M Sanders, Markus J Seibel, Rebecca S Mason.   

Abstract

The prevalence of vitamin D deficiency varies, with the groups at greatest risk including housebound, community-dwelling older and/or disabled people, those in residential care, dark-skinned people (particularly those modestly dressed), and other people who regularly avoid sun exposure or work indoors. Most adults are unlikely to obtain more than 5%-10% of their vitamin D requirement from dietary sources. The main source of vitamin D for people residing in Australia and New Zealand is exposure to sunlight. A serum 25-hydroxyvitamin D (25-OHD) level of ≥ 50 nmol/L at the end of winter (10-20 nmol/L higher at the end of summer, to allow for seasonal decrease) is required for optimal musculoskeletal health. Although it is likely that higher serum 25-OHD levels play a role in the prevention of some disease states, there is insufficient evidence from randomised controlled trials to recommend higher targets. For moderately fair-skinned people, a walk with arms exposed for 6-7 minutes mid morning or mid afternoon in summer, and with as much bare skin exposed as feasible for 7-40 minutes (depending on latitude) at noon in winter, on most days, is likely to be helpful in maintaining adequate vitamin D levels in the body. When sun exposure is minimal, vitamin D intake from dietary sources and supplementation of at least 600 IU (15 µg) per day for people aged ≤ 70 years and 800 IU (20 µg) per day for those aged > 70 years is recommended. People in high-risk groups may require higher doses. There is good evidence that vitamin D plus calcium supplementation effectively reduces fractures and falls in older men and women.

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Year:  2012        PMID: 22708765     DOI: 10.5694/mja11.10301

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  91 in total

1.  Vitamin D levels in primary growth hormone deficiency disorder Prader-Willi syndrome.

Authors:  Louise Purtell; Alexander Viardot; Lesley V Campbell
Journal:  Endocrine       Date:  2016-02-12       Impact factor: 3.633

2.  Cross-sectional and longitudinal associations between the active vitamin D metabolite (1,25 dihydroxyvitamin D) and haemoglobin levels in older Australian men: the Concord Health and Ageing in Men Project.

Authors:  Vasant Hirani; Robert G Cumming; Fiona Blyth; Vasi Naganathan; David G Le Couteur; Louise M Waite; David J Handelsman; Markus J Seibel
Journal:  Age (Dordr)       Date:  2015-02-04

3.  Application of the stockholm hierarchy to defining the quality of reference intervals and clinical decision limits.

Authors:  Ken Sikaris
Journal:  Clin Biochem Rev       Date:  2012-11

4.  Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.

Authors:  D Anderson; B J Holt; C E Pennell; P G Holt; P H Hart; J M Blackwell
Journal:  Genes Immun       Date:  2014-09-11       Impact factor: 2.676

5.  Cut-points for associations between vitamin D status and multiple musculoskeletal outcomes in middle-aged women.

Authors:  F Wu; K Wills; L L Laslett; B Oldenburg; M J Seibel; G Jones; T Winzenberg
Journal:  Osteoporos Int       Date:  2016-09-09       Impact factor: 4.507

6.  Vitamin D Supplementation in Tasmanian Nursing Home Residents.

Authors:  Colin M Curtain; Mackenzie Williams; Justin M Cousins; Gregory M Peterson; Tania Winzenberg
Journal:  Drugs Aging       Date:  2016-10       Impact factor: 3.923

Review 7.  Vitamin D and bone health: Epidemiologic studies.

Authors:  Peter R Ebeling
Journal:  Bonekey Rep       Date:  2014-03-05

8.  Associations between vitamin D metabolites, antiretroviral therapy and bone mineral density in people with HIV.

Authors:  K M Klassen; M G Kimlin; C K Fairley; S Emery; P H Anderson; P R Ebeling
Journal:  Osteoporos Int       Date:  2015-12-11       Impact factor: 4.507

9.  Exposure to UV Wavelengths in Sunlight Suppresses Immunity. To What Extent is UV-induced Vitamin D3 the Mediator Responsible?

Authors:  Prue H Hart; Shelley Gorman
Journal:  Clin Biochem Rev       Date:  2013-02

10.  The relationship between solar UV exposure, serum vitamin D levels and serum prostate-specific antigen levels, in men from New South Wales, Australia: the CHAMP study.

Authors:  Visalini Nair-Shalliker; David P Smith; Mark Clements; Vasikaran Naganathan; Melisa Litchfield; Louise Waite; David Handelsman; Markus J Seibel; Robert Cumming; Bruce K Armstrong
Journal:  World J Urol       Date:  2013-11-05       Impact factor: 4.226

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