Literature DB >> 22708546

Cytotoxic and leishmanicidal properties of garcinielliptone FC, a prenylated benzophenone from Platonia insignis.

Joaquim S Costa Júnior1, Antonia Amanda Cardoso de Almeida, Alexandre de Barros Falcão Ferraz, Raíssa Rebés Rossatto, Teresinha G Silva, Paulo B N Silva, Gardenia C G Militão, Antonia Maria das Graças Lopes Citó, Lorena Citó Lopes Resende Santana, Fernando Aécio de Amorim Carvalho, Rivelilson M Freitas.   

Abstract

Garcinielliptone FC (GFC), a natural prenylated benzophenone, was extracted from Platonia insignis Mart. (Clusiaceae), a native plant commonly known as bacuri and used in traditional Brazilian medicine for the treatment of skin diseases. The aim of this study was to evaluate the cytotoxic and leishmanicidal effects of GFC using in vitro models. The experimental data demonstrated that the polyisoprenylated benzophenone GFC possesses cytotoxic and leishmanicidal activities.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22708546     DOI： 10.1080/14786419.2012.695363

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  5 in total

1.  Antifungal and Antivirulence Activities of Hydroalcoholic Extract and Fractions of Platonia insignis Leaves against Vaginal Isolates of Candida Species.

Authors:  Anderson França da Silva; Cláudia Quintino da Rocha; Luís Cláudio Nascimento da Silva; Alexsander Rodrigues Carvalho Júnior; Iven Neylla Farias Vale Mendes; Andrea Borges de Araruna; Elizangela Pestana Motta; Rayssa de Sousa Silva; Carmem Duarte Lima Campos; Josivan Regis Farias; Aluísio da Silva Oliveira; Douglas Henrique Dos Santos Silva; Flávia Raquel F Nascimento; Rosane Nassar Meireles Guerra; Cristina Andrade Monteiro
Journal:  Pathogens       Date:  2020-01-28

2.  Effects of "Bacuri" Seed Butter (Platonia insignis Mart.) on Metabolic Parameters in Hamsters with Diet-Induced Hypercholesterolemia.

Authors:  Geovanni de Morais Lima; Ana Karolinne da Silva Brito; Luciana Melo de Farias; Lays Arnaud Rosal Lopes Rodrigues; Cristian Francisco de Carvalho Pereira; Simone Kelly Rodrigues Lima; Karoline de Macedo Gonçalves Frota; Márcia Dos Santos Rizzo; Paulo Humberto Moreira Nunes; Massimo Lucarini; Alessandra Durazzo; Daniel Dias Rufino Arcanjo; Maria do Carmo de Carvalho E Martins
Journal:  Evid Based Complement Alternat Med       Date:  2021-12-06       Impact factor: 2.629

3.  Platonia insignis Mart., a Brazilian Amazonian Plant: The Stem Barks Extract and Its Main Constituent Lupeol Exert Antileishmanial Effects Involving Macrophages Activation.

Authors:  Adriana Cunha Souza; Michel Muálem de Moraes Alves; Lucas Moreira Brito; Luciano Gomes De Castro Oliveira; Enoque Pereira Costa Sobrinho-Júnior; Isabella Cristhina Gonçalves Costa; Sâmya Danielle Lima Freitas; Klinger Antonio da Franca Rodrigues; Mariana Helena Chaves; Daniel Dias Rufino Arcanjo; Fernando Aécio de Amorim Carvalho
Journal:  Evid Based Complement Alternat Med       Date:  2017-08-09       Impact factor: 2.629

4.  Amazonian Bacuri (Platonia insignis Mart.) Fruit Waste Valorisation Using Response Surface Methodology.

Authors:  Klenicy K L Yamaguchi; David S Dias; Carlos Victor Lamarão; Karen F A Castelo; Max S Lima; Ananda S Antonio; Attilio Converti; Emerson S Lima; Valdir F Veiga-Junior
Journal:  Biomolecules       Date:  2021-11-25

5.  New Alpha-Amylase Inhibitory Metabolites from Pericarps of Garcinia mangostana.

Authors:  Nabil Abdulhafiz Alhakamy; Gamal Abdallah Mohamed; Usama Ahmed Fahmy; Basma Ghazi Eid; Osama Abdelhakim Aly Ahmed; Mohammed Wanees Al-Rabia; Amgad Ibrahim Mansour Khedr; Mohammed Zahid Nasrullah; Sabrin Ragab Mohamed Ibrahim
Journal:  Life (Basel)       Date:  2022-03-07
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.