Literature DB >> 22707679

Adenocarcinoma of lung masquerading as systemic auto-immune disease.

Kushal Naha1, Sayali Thakare, G Vivek, Mukhyaprana Prabhu.   

Abstract

A 40-year-old previously healthy male presented with acute onset painless dimness of vision in both eyes since the past week and low-grade fever, anorexia and weight loss for the past 1 month. He had been evaluated at a local hospital and diagnosed to have a posterior cerebral artery territory infarct on the left side on the strength of cranial CT. Shortly after receiving antiplatelets and warfarin he had developed severe coagulopathy as evidenced by haematemesis, epistaxis and haematuria. Preliminary investigation revealed prolonged clotting parameters, renal failure and anaemia. Cerebral MRI showed multiple areas of cortical haemorrhage. In the course of his hospital stay, he developed further stigmata of auto-immunity including Coomb's positive haemolytic anaemia, recurrent venous thromboses and a palpable purpuric truncal rash. He was eventually diagnosed to have an adenocarcinoma of the lung, and was subsequently referred to an oncologist for further therapy.

Entities:  

Mesh:

Year:  2012        PMID: 22707679      PMCID: PMC3387439          DOI: 10.1136/bcr.02.2012.5822

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

Review 1.  Neoplastic and paraneoplastic vasculitis, vasculopathy, and hypercoagulability.

Authors:  Hyon Ju Park; Prabha Ranganathan
Journal:  Rheum Dis Clin North Am       Date:  2011-11       Impact factor: 2.670

2.  Paraneoplastic syndromes in 68 cases of resectable non-small cell lung carcinoma: can they help in early detection?

Authors:  N Campanella; A Moraca; M Pergolini; W Daher; A Fianchini; A Sabbatini; A Brunelli; M Al-Refai
Journal:  Med Oncol       Date:  1999-07       Impact factor: 3.064

Review 3.  Cancer and autoimmunity: autoimmune and rheumatic features in patients with malignancies.

Authors:  M Abu-Shakra; D Buskila; M Ehrenfeld; K Conrad; Y Shoenfeld
Journal:  Ann Rheum Dis       Date:  2001-05       Impact factor: 19.103

Review 4.  Paraneoplastic vasculitis in patients with solid tumors: report of 15 cases.

Authors:  Roser Solans-Laqué; Josep Angel Bosch-Gil; Carmen Pérez-Bocanegra; Albert Selva-O'Callaghan; Carmen P Simeón-Aznar; Miquel Vilardell-Tarres
Journal:  J Rheumatol       Date:  2007-12-15       Impact factor: 4.666

5.  Vasculitides associated with malignancies: analysis of sixty patients.

Authors:  Olivier Fain; Mohamed Hamidou; Patrice Cacoub; Bertrand Godeau; Bertrand Wechsler; Jacques Pariès; Jérôme Stirnemann; Anne-Sophie Morin; Marc Gatfosse; Thomas Hanslik; Nadia Belmatoug; Olivier Blétry; Ramiro Cevallos; Isabelle Delevaux; Evelyne Fisher; Gilles Hayem; Gérard Kaplan; Claire Le Hello; Luc Mouthon; Claire Larroche; Véra Lemaire; Anne-Marie Piette; Jean-Charles Piette; Thierry Ponge; Xavier Puechal; Jérôme Rossert; Françoise Sarrot-Reynauld; Didier Sicard; Jean-Marc Ziza; Marcel-Francis Kahn; Loïc Guillevin
Journal:  Arthritis Rheum       Date:  2007-12-15
  5 in total

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