Literature DB >> 22707514

Fertility preservation in women undergoing treatment for breast cancer in the UK: a questionnaire study.

Judy W King1, Melanie C Davies, Nicola Roche, Jacinta M Abraham, Alison L Jones.   

Abstract

OBJECTIVE: Fertility preservation is an important survivorship issue for women treated for breast cancer. The aim of this work was to examine the referral practices of health care professionals who treat women with breast cancer in the United Kingdom, and to investigate their understanding and knowledge of the fertility preservation options available.
METHOD: An invitation to participate in a confidential, online questionnaire was e-mailed to surgeons, oncologists, and clinical nurse specialists who manage patients with breast cancer in the United Kingdom.
RESULTS: n = 306 respondents. Factors which influenced whether fertility preservation options were discussed with a patient included the following: patient's age (78%), final tumor/nodes/metastasis status (37.9%); concern that fertility preservation would delay chemotherapy (37.3%); whether the patient had children (33.5%) or a partner (24.7%); estrogen receptor expression (22.6%), lack of knowledge regarding the available options (20.9%); and concern that fertility preservation would compromise the success of cancer treatment (19.8%). Twenty-seven percent did not know whether fertility preservation was available for their patients on the National Health Service. Nearly half (49.4%) of respondents said that gonadotropin-releasing hormone agonists were used for fertility preservation outside the setting of a clinical trial. Knowledge regarding the available options varied according to different members of the multidisciplinary team, with consultant oncologists better informed than consultant surgeons or clinical nurse specialists (p < .05).
CONCLUSIONS: Many health care professionals have incomplete knowledge regarding the local arrangements for fertility preservation for patients with breast cancer. This may result in patients receiving inadequate or conflicting information regarding fertility preservation.

Entities:  

Mesh:

Year:  2012        PMID: 22707514      PMCID: PMC3399645          DOI: 10.1634/theoncologist.2012-0064

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  26 in total

1.  Further evidence on the safety and success of ovarian stimulation with letrozole and tamoxifen in breast cancer patients undergoing in vitro fertilization to cryopreserve their embryos for fertility preservation.

Authors:  Kutluk Oktay
Journal:  J Clin Oncol       Date:  2005-05-23       Impact factor: 44.544

Review 2.  Fertility preservation in young women undergoing breast cancer therapy.

Authors:  Murat Sonmezer; Kutluk Oktay
Journal:  Oncologist       Date:  2006-05

Review 3.  The emergence of a new interdiscipline: oncofertility.

Authors:  Teresa K Woodruff
Journal:  Cancer Treat Res       Date:  2007

4.  Fertility preservation in breast cancer patients: a prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation.

Authors:  Kutluk Oktay; Erkan Buyuk; Natalie Libertella; Munire Akar; Zev Rosenwaks
Journal:  J Clin Oncol       Date:  2005-04-11       Impact factor: 44.544

5.  Gonadotropin-releasing hormone analogues added to adjuvant chemotherapy protect ovarian function and improve clinical outcomes in young women with early breast carcinoma.

Authors:  Francesco Recchia; Gaetano Saggio; Giovanna Amiconi; Anna Di Blasio; Alisia Cesta; Giampiero Candeloro; Silvio Rea
Journal:  Cancer       Date:  2006-02-01       Impact factor: 6.860

6.  Sexual dysfunction related to the treatment of young women with breast cancer.

Authors:  Rose Townley Bakewell; Deborah L Volker
Journal:  Clin J Oncol Nurs       Date:  2005-12       Impact factor: 1.027

7.  American Society of Clinical Oncology recommendations on fertility preservation in cancer patients.

Authors:  Stephanie J Lee; Leslie R Schover; Ann H Partridge; Pasquale Patrizio; W Hamish Wallace; Karen Hagerty; Lindsay N Beck; Lawrence V Brennan; Kutluk Oktay
Journal:  J Clin Oncol       Date:  2006-05-01       Impact factor: 44.544

8.  Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression.

Authors:  Carey K Anders; David S Hsu; Gloria Broadwater; Chaitanya R Acharya; John A Foekens; Yi Zhang; Yixin Wang; P Kelly Marcom; Jeffrey R Marks; Phillip G Febbo; Joseph R Nevins; Anil Potti; Kimberly L Blackwell
Journal:  J Clin Oncol       Date:  2008-07-10       Impact factor: 44.544

9.  Age of menopause among women who remain premenopausal following treatment for early breast cancer: long-term results from International Breast Cancer Study Group Trials V and VI.

Authors:  Ann Partridge; Shari Gelber; Richard D Gelber; Monica Castiglione-Gertsch; Aron Goldhirsch; Eric Winer
Journal:  Eur J Cancer       Date:  2007-05-18       Impact factor: 9.162

Review 10.  Cancer and fertility preservation: fertility preservation in breast cancer patients.

Authors:  Theodoros Maltaris; Michael Weigel; Andreas Mueller; Marcus Schmidt; Rudolf Seufert; Franz Fischl; Heinz Koelbl; Ralf Dittrich
Journal:  Breast Cancer Res       Date:  2008-04-29       Impact factor: 6.466

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  15 in total

1.  Perception and needs of reproductive specialists with regard to fertility preservation of young breast cancer patients.

Authors:  Chikako Shimizu; Tomoyasu Kato; Nobuko Tamura; Hiroko Bando; Yoshimasa Asada; Yuri Mizota; Seiichiro Yamamoto; Yasuhiro Fujiwara
Journal:  Int J Clin Oncol       Date:  2014-02-22       Impact factor: 3.402

2.  Prospective study of fertility concerns and preservation strategies in young women with breast cancer.

Authors:  Kathryn J Ruddy; Shari I Gelber; Rulla M Tamimi; Elizabeth S Ginsburg; Lidia Schapira; Steven E Come; Virginia F Borges; Meghan E Meyer; Ann H Partridge
Journal:  J Clin Oncol       Date:  2014-02-24       Impact factor: 44.544

3.  Therapy choices and quality of life in young breast cancer survivors: a short-term follow-up.

Authors:  Marie Catherine Lee; Rajendra S Bhati; Edina E von Rottenthaler; Angela M Reagan; Sloan B Karver; Richard R Reich; Gwendolyn P Quinn
Journal:  Am J Surg       Date:  2013-09-06       Impact factor: 2.565

4.  Occurrence and recall rates of fertility discussions with young breast cancer patients.

Authors:  Rahul Banerjee; Ekaterini Tsiapali
Journal:  Support Care Cancer       Date:  2015-05-13       Impact factor: 3.603

Review 5.  Healthcare professionals' views on discussing fertility preservation with young cancer patients: a mixed method systematic review of the literature.

Authors:  Cecilia Vindrola-Padros; Karen E Dyer; John Cyrus; Irene Machowa Lubker
Journal:  Psychooncology       Date:  2016-02-18       Impact factor: 3.894

Review 6.  Non-physician's challenges in sexual and reproductive health care provision for women of reproductive age with cancer: a scoping review of barriers and facilitators.

Authors:  Qi Chen; Emma Carpenter; Kari White
Journal:  Support Care Cancer       Date:  2022-10-10       Impact factor: 3.359

7.  Assessing information and service needs of young adults with cancer at a single institution: the importance of information on cancer diagnosis, fertility preservation, diet, and exercise.

Authors:  Abha A Gupta; Kim Edelstein; Alisha Albert-Green; Norma D'Agostino
Journal:  Support Care Cancer       Date:  2013-04-21       Impact factor: 3.603

8.  Young female cancer survivors' use of fertility care after completing cancer treatment.

Authors:  Jayeon Kim; Jennifer E Mersereau; H Irene Su; Brian W Whitcomb; Vanessa L Malcarne; Jessica R Gorman
Journal:  Support Care Cancer       Date:  2016-03-04       Impact factor: 3.603

9.  Pediatric Oncology Providers' Attitudes and Practice Patterns Regarding Fertility Preservation in Adolescent Male Cancer Patients.

Authors:  Amanda Fuchs; James A Kashanian; Marla L Clayman; Yasmin Gosiengfiao; Barbara Lockart; Teresa K Woodruff; Robert E Brannigan
Journal:  J Pediatr Hematol Oncol       Date:  2016-03       Impact factor: 1.289

10.  Fertility issues in young breast cancer patients: what women want.

Authors:  Matteo Lambertini; Ana Catarina Pinto; Lucia Del Mastro
Journal:  J Thorac Dis       Date:  2014-06       Impact factor: 2.895

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