Literature DB >> 22707491

A hidden cause of upper gastrointestinal bleeding.

S Ali1, J Addley, S Johnston, D Carey, D McManus.   

Abstract

Gastrointestinal stromal tumours (GISTs) are a subset of gastrointestinal (GI) mesenchymal tumours of varying differentiation and represent 1-3% of all gastrointestinal malignancies--70% occur in the stomach. Previously, these tumours were classified as GI leiomyomas, leiomyosarcomas, leiomyoblastomas or schwannomas on the basis of histological findings and the fact that these tumours apparently originate in the muscularis propria layer of the intestinal wall. With the advent of immunohistochemical staining techniques and ultrastructural evaluation, GISTs are now recognised as a distinct group of mesenchymal tumours. Most cases are sporadic although some families with hereditary GISTs have been described. We report a coinicidental finding of GIST in an asymptomatic patient and subsequent management.

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Year:  2011        PMID: 22707491      PMCID: PMC3062815          DOI: 10.1136/bcr.01.2010.2674

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  25 in total

1.  Epithelioid hemangioendothelioma of skin and soft tissues: clinicopathologic and immunohistochemical study of 30 cases.

Authors:  T Mentzel; A Beham; E Calonje; D Katenkamp; C D Fletcher
Journal:  Am J Surg Pathol       Date:  1997-04       Impact factor: 6.394

2.  Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival.

Authors:  R P DeMatteo; J J Lewis; D Leung; S S Mudan; J M Woodruff; M F Brennan
Journal:  Ann Surg       Date:  2000-01       Impact factor: 12.969

Review 3.  Gastrointestinal stromal tumours.

Authors:  M Miettinen; M Sarlomo-Rikala; J Lasota
Journal:  Ann Chir Gynaecol       Date:  1998

Review 4.  Gastrointestinal sarcoma (GIST)--a review of surgical management.

Authors:  T Lehnert
Journal:  Ann Chir Gynaecol       Date:  1998

5.  Epithelioid haemangioendothelioma presenting as a gastric polyp.

Authors:  K C Lee; W F Ng; J K Chan
Journal:  Histopathology       Date:  1988-03       Impact factor: 5.087

6.  An immunohistochemical and clinicopathological study of gastrointestinal stromal tumors.

Authors:  K Tazawa; K Tsukada; H Makuuchi; Y Tsutsumi
Journal:  Pathol Int       Date:  1999-09       Impact factor: 2.534

Review 7.  [Gastrointestinal stroma tumor: a surgical oncology problem child?].

Authors:  S Irani; M Fartab
Journal:  Chirurg       Date:  1999-03       Impact factor: 0.955

Review 8.  Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis.

Authors:  Markku Miettinen; Jerzy Lasota
Journal:  Arch Pathol Lab Med       Date:  2006-10       Impact factor: 5.534

9.  Surgical treatment of gastric gastrointestinal stromal tumors: analysis of 92 operated patients.

Authors:  I-Rue Lai; Chiung-Nien Chen; Ming-Tsan Lin; Po-Huang Lee
Journal:  Dig Surg       Date:  2008-06-23       Impact factor: 2.588

10.  Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas.

Authors:  J Lasota; M Jasinski; M Sarlomo-Rikala; M Miettinen
Journal:  Am J Pathol       Date:  1999-01       Impact factor: 4.307

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