Literature DB >> 22707392

ortho-Quinone methides in natural product synthesis.

Nicky J Willis1, Christopher D Bray.   

Abstract

ortho-Quinone methides (o-QMs) are emerging as highly useful intermediates, the inherent reactivity of which can be used in linchpin reactions for the construction of complex natural products. This review encompasses the major contributions in this field, exemplifying the major strategies and reactivity modes which can be applied.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 22707392     DOI： 10.1002/chem.201200619

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  32 in total

1.  Gold(I)-Mediated Cycloisomerization/Cycloaddition Enables Bioinspired Syntheses of Neonectrolides B-E and Analogues.

Authors:  Thomas J Purgett; Matthew W Dyer; Bryce Bickel; James McNeely; John A Porco
Journal:  J Am Chem Soc       Date:  2019-09-12       Impact factor: 15.419

2.  Harnessing quinone methides: total synthesis of (±)-vaticanol A.

Authors:  Tue H Jepsen; Stephen B Thomas; Yunqing Lin; Christos I Stathakis; Irene de Miguel; Scott A Snyder
Journal:  Angew Chem Int Ed Engl       Date:  2014-05-19       Impact factor: 15.336

3.  Chemoenzymatic o-Quinone Methide Formation.

Authors:  Tyler J Doyon; Jonathan C Perkins; Summer A Baker Dockrey; Evan O Romero; Kevin C Skinner; Paul M Zimmerman; Alison R H Narayan
Journal:  J Am Chem Soc       Date:  2019-12-16       Impact factor: 15.419

4.  Enantioselective Phenolic α-Oxidation Using H2O2 via an Unusual Double Dearomatization Mechanism.

Authors:  Michael F McLaughlin; Elisabetta Massolo; Shubin Liu; Jeffrey S Johnson
Journal:  J Am Chem Soc       Date:  2019-01-30       Impact factor: 15.419

5.  Development of an alkaloid-pyrone annulation: synthesis of pleiomaltinine.

Authors:  Robert E Ziegler; Shin-Jowl Tan; Toh-Seok Kam; John A Porco
Journal:  Angew Chem Int Ed Engl       Date:  2012-08-15       Impact factor: 15.336

6.  A dual Lewis base activation strategy for enantioselective carbene-catalyzed annulations.

Authors:  Javier Izquierdo; Ane Orue; Karl A Scheidt
Journal:  J Am Chem Soc       Date:  2013-07-11       Impact factor: 15.419

7.  Multicomponent Condensation Reactions via ortho-Quinone Methides.

Authors:  Emily E Allen; Calvin Zhu; James S Panek; Scott E Schaus
Journal:  Org Lett       Date:  2017-03-30       Impact factor: 6.005

8.  Directing Quinone Methide-Dependent Alkylation and Cross-Linking of Nucleic Acids with Quaternary Amines.

Authors:  Mark A Hutchinson; Blessing D Deeyaa; Shane R Byrne; Sierra J Williams; Steven E Rokita
Journal:  Bioconjug Chem       Date:  2020-04-23       Impact factor: 4.774

9.  Evolution of a Strategy for the Enantioselective Total Synthesis of (+)-Psiguadial B.

Authors:  Lauren M Chapman; Jordan C Beck; Caitlin R Lacker; Linglin Wu; Sarah E Reisman
Journal:  J Org Chem       Date:  2018-05-18       Impact factor: 4.354

10.  Enantioselective Multicomponent Condensation Reactions of Phenols, Aldehydes, and Boronates Catalyzed by Chiral Biphenols.

Authors:  Keith S Barbato; Yi Luan; Daniele Ramella; James S Panek; Scott E Schaus
Journal:  Org Lett       Date:  2015-11-18       Impact factor: 6.005
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