Literature DB >> 22707058

α-Ketoglutaric acid production by Yarrowia lipolytica and its regulation.

Svetlana V Kamzolova1, Maria N Chiglintseva, Julia N Lunina, Igor G Morgunov.   

Abstract

The yeast Yarrowia lipolytica VKM Y-2412 was selected as a prospective producer of α-ketoglutaric acid (KGA) from ethanol. The following peculiarities were found: (1) the intensive KGA production occurred only under the limitation of cell growth by thiamine and the excess of ethanol and nitrogen, (2) the production of KGA from ethanol required increased amount of zinc and iron ions, and (3) KGA production increased significantly with a high aeration at pH medium equal to 3.5. Under optimal conditions, the Y. lipolytica VKM Y-2412 produced up to 172 g l(-1) of KGA with the mass yield coefficient of 0.70 g g(-1).

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Year:  2012        PMID: 22707058     DOI: 10.1007/s00253-012-4222-x

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  7 in total

1.  Modelling of the Citric Acid Production from Crude Glycerol by Wild-Type Yarrowia lipolytica DSM 8218 Using Response Surface Methodology (RSM).

Authors:  Romina Giacomobono; Roberto Albergo; Vito Valerio; Antonio Caporusso; Isabella De Bari
Journal:  Life (Basel)       Date:  2022-04-21

2.  Identification and application of keto acids transporters in Yarrowia lipolytica.

Authors:  Hongwei Guo; Peiran Liu; Catherine Madzak; Guocheng Du; Jingwen Zhou; Jian Chen
Journal:  Sci Rep       Date:  2015-01-30       Impact factor: 4.379

3.  Mineral supplementation increases erythrose reductase activity in erythritol biosynthesis from glycerol by Yarrowia lipolytica.

Authors:  Ludwika Tomaszewska; Waldemar Rymowicz; Anita Rywińska
Journal:  Appl Biochem Biotechnol       Date:  2014-02-01       Impact factor: 2.926

4.  Fermentation Conditions and Media Optimization for Isocitric Acid Production from Ethanol by Yarrowia lipolytica.

Authors:  Svetlana V Kamzolova; Roman V Shamin; Nadezda N Stepanova; Grigorii I Morgunov; Julia N Lunina; Ramil K Allayarov; Vladimir A Samoilenko; Igor G Morgunov
Journal:  Biomed Res Int       Date:  2018-02-07       Impact factor: 3.411

5.  Heterologous overexpression of bacterial hemoglobin VHb improves erythritol biosynthesis by yeast Yarrowia lipolytica.

Authors:  Aleksandra M Mirończuk; Katarzyna E Kosiorowska; Anna Biegalska; Magdalena Rakicka-Pustułka; Mateusz Szczepańczyk; Adam Dobrowolski
Journal:  Microb Cell Fact       Date:  2019-10-15       Impact factor: 5.328

Review 6.  Sugar Alcohols and Organic Acids Synthesis in Yarrowia lipolytica: Where Are We?

Authors:  Patrick Fickers; Hairong Cheng; Carol Sze Ki Lin
Journal:  Microorganisms       Date:  2020-04-15

7.  Application of Stable Isotope Tracing to Elucidate Metabolic Dynamics During Yarrowia lipolytica α-Ionone Fermentation.

Authors:  Jeffrey J Czajka; Shrikaar Kambhampati; Yinjie J Tang; Yechun Wang; Doug K Allen
Journal:  iScience       Date:  2020-01-22
  7 in total

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