Akinlabi O Ogunleye1, Steve A Carlson. 1. Department of Veterinary Microbiology and Parasitology, University of Ibadan, Ibadan, Oyo State, Nigeria. ao.ogunleye@mail.ui.edu.ng
Abstract
INTRODUCTION: Salmonella enterica serotype Kentucky was isolated from septic poultry in Nigeria. The objective of this study was to characterize this isolate by screening for SGI1 and hyper-virulence. METHODOLOGY: The strain was characterized by identification of Salmonella genomic island 1 (SGI1) through a PCR assay and we used a tissue culture invasion assay to assess protozoa-mediated hyper-invasion. RESULTS: Salmonella genomic island 1 (SGI1) was identified in the strain along with an SGI1 gene (SO13) implicated in hyper-virulence. Protozoa-mediated hyper-invasiveness was also documented in the strain. CONCLUSION: The hyper-invasion is concordant with this emerging strain's ability to cause fowl paratyphoid.
INTRODUCTION:Salmonella enterica serotype Kentucky was isolated from septic poultry in Nigeria. The objective of this study was to characterize this isolate by screening for SGI1 and hyper-virulence. METHODOLOGY: The strain was characterized by identification of Salmonella genomic island 1 (SGI1) through a PCR assay and we used a tissue culture invasion assay to assess protozoa-mediated hyper-invasion. RESULTS:Salmonella genomic island 1 (SGI1) was identified in the strain along with an SGI1 gene (SO13) implicated in hyper-virulence. Protozoa-mediated hyper-invasiveness was also documented in the strain. CONCLUSION: The hyper-invasion is concordant with this emerging strain's ability to cause fowl paratyphoid.
Authors: Idowu Oluwabunmi Fagbamila; Lisa Barco; Marzia Mancin; Jacob Kwaga; Sati Samuel Ngulukun; Paola Zavagnin; Antonia Anna Lettini; Monica Lorenzetto; Paul Ayuba Abdu; Junaidu Kabir; Jarlath Umoh; Antonia Ricci; Maryam Muhammad Journal: PLoS One Date: 2017-03-09 Impact factor: 3.240