OBJECTIVES: To assess fat distribution, prevalence of obesity, and the metabolic syndrome among diverse 6-13-year-old Colorado youth to better understand racial/ethnic influences on adiposity and metabolic syndrome. STUDY DESIGN: We measured body mass index, subscapular-to-triceps skinfold ratio, waist circumference, dietary fat, and physical activity in 422 youth (47% non-Hispanic White, 44% Hispanic, and 9% African-American). Visceral adipose tissue, subcutaneous adipose tissue, and intramyocellular lipid were measured with magnetic resonance techniques. Multiple-linear regression was used to assess associations between race/ethnicity and adiposity patterns. RESULTS: Hispanic and African-American youth had a higher prevalence of obesity and metabolic syndrome compared with non-Hispanic White youth. Both groups displayed a more centralized fat distribution and larger volumes of subcutaneous tissue, compared with non-Hispanic White youth. After controlling for body mass index, these differences were attenuated, and for a given body size, African-American youth showed significantly lower visceral adipose tissue than non-Hispanic White youth. However, both Hispanic and African-American youth showed higher intermyocellular lipid in skeletal muscle compared with non-Hispanic Whites, independent of body size. CONCLUSIONS: Racial/ethnic minorities experience higher overall adiposity, and may also have an increased risk for early development of metabolic syndrome relative to non-Hispanic White youth, beyond their increased obesity risk.
OBJECTIVES: To assess fat distribution, prevalence of obesity, and the metabolic syndrome among diverse 6-13-year-old Colorado youth to better understand racial/ethnic influences on adiposity and metabolic syndrome. STUDY DESIGN: We measured body mass index, subscapular-to-triceps skinfold ratio, waist circumference, dietary fat, and physical activity in 422 youth (47% non-Hispanic White, 44% Hispanic, and 9% African-American). Visceral adipose tissue, subcutaneous adipose tissue, and intramyocellular lipid were measured with magnetic resonance techniques. Multiple-linear regression was used to assess associations between race/ethnicity and adiposity patterns. RESULTS: Hispanic and African-American youth had a higher prevalence of obesity and metabolic syndrome compared with non-Hispanic White youth. Both groups displayed a more centralized fat distribution and larger volumes of subcutaneous tissue, compared with non-Hispanic White youth. After controlling for body mass index, these differences were attenuated, and for a given body size, African-American youth showed significantly lower visceral adipose tissue than non-Hispanic White youth. However, both Hispanic and African-American youth showed higher intermyocellular lipid in skeletal muscle compared with non-Hispanic Whites, independent of body size. CONCLUSIONS: Racial/ethnic minorities experience higher overall adiposity, and may also have an increased risk for early development of metabolic syndrome relative to non-Hispanic White youth, beyond their increased obesity risk.
Authors: Ram Weiss; Sara E Taksali; Sylvie Dufour; Catherine W Yeckel; Xenophon Papademetris; Gary Cline; William V Tamborlane; James Dziura; Gerald I Shulman; Sonia Caprio Journal: J Clin Endocrinol Metab Date: 2005-03-29 Impact factor: 5.958
Authors: Sara E Taksali; Sonia Caprio; James Dziura; Sylvie Dufour; Anna M G Calí; T Robin Goodman; Xenophon Papademetris; Tania S Burgert; Bridget M Pierpont; Mary Savoye; Melissa Shaw; Aisha A Seyal; Ram Weiss Journal: Diabetes Date: 2007-10-31 Impact factor: 9.461
Authors: Tanya L Alderete; Rima Habre; Claudia M Toledo-Corral; Kiros Berhane; Zhanghua Chen; Frederick W Lurmann; Marc J Weigensberg; Michael I Goran; Frank D Gilliland Journal: Diabetes Date: 2017-01-30 Impact factor: 9.461
Authors: Peter M Wolfgram; Ellen L Connor; Jennifer L Rehm; Jens C Eickhoff; Wei Zha; Scott B Reeder; David B Allen Journal: Horm Res Paediatr Date: 2015-09-10 Impact factor: 2.852
Authors: Maggie A Stanislawski; Jessica Shaw; Elizabeth Litkowski; Ethan M Lange; Wei Perng; Dana Dabelea; Leslie A Lange Journal: J Pediatr Date: 2020-03-04 Impact factor: 4.406
Authors: Shan Luo; Ana Romero; Tanja C Adam; Houchun H Hu; John Monterosso; Kathleen A Page Journal: Obesity (Silver Spring) Date: 2013-05-29 Impact factor: 5.002