Literature DB >> 22703331

The recombinant human chorionic gonadotropin prefilled pen: results of patient and nurse human factors usability testing.

Helen Saunders1, Joan C Schertz, Clara Hecker, Barbara Lang, Pablo Arriagada.   

Abstract

OBJECTIVES: The first prefilled pen for administration of recombinant human chorionic gonadotropin (r-hCG) has been developed. Usability testing was undertaken to evaluate the risk of dosing errors versus the existing r-hCG prefilled syringe, and assess function and handling of the pen.
METHODS: Infertile women who were trying to conceive, and specialist nurses, were recruited in Germany. Usability goals were defined and categorized as critical or functional operational goals. Individual, non-interventional, standardized, usability tests (including ease-of-use assessment) were performed with patients and nurses. Cumulative test scores for critical operations were compared. Non-standardized qualitative analyses of nurse-patient training sessions were performed.
RESULTS: The cumulative test score for the r-hCG prefilled pen was better than that of the existing prefilled syringe, so it was concluded that the overall risk of dosing errors was not higher with the pen. The ease of use of the pen was rated favorably by patients and nurses. Both user groups were confident that they could inject the correct dose using the pen.
CONCLUSIONS: The overall risk of dosing errors was not higher with the r-hCG prefilled pen than the existing prefilled syringe. The ease-of-use of the r-hCG prefilled pen was rated favorably by patients and nurses.

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Year:  2012        PMID: 22703331     DOI: 10.1517/17425247.2012.698607

Source DB:  PubMed          Journal:  Expert Opin Drug Deliv        ISSN: 1742-5247            Impact factor:   6.648


  4 in total

Review 1.  Gonadotropin therapy in assisted reproduction: an evolutionary perspective from biologics to biotech.

Authors:  Rogério de Barros F Leão; Sandro C Esteves
Journal:  Clinics (Sao Paulo)       Date:  2014       Impact factor: 2.365

2.  Satisfaction and usability of the recombinant chorionic gonadotropin prefilled pen: a survey in Italy.

Authors:  Chiara Dallagiovanna; Laura Mensi; Luca Di Gesaro; Irene La Vecchia; Marco Reschini
Journal:  Drugs Context       Date:  2022-01-26

3.  Single-arm, observational study of the ease of use of a redesigned pen device to deliver recombinant human follicle-stimulating hormone (follitropin alfa) for assisted reproductive technology treatment.

Authors:  Peter J Illingworth; Robert Lahoud; Frank Quinn; Kendal Chidwick; Claire Wilkinson; Gavin Sacks
Journal:  Patient Prefer Adherence       Date:  2014-06-05       Impact factor: 2.711

4.  Analysis of patient and nurse preferences for self-administered FSH injection devices in select European markets.

Authors:  Pierre Zitoun; Jaya Parikh; Martine Nijs; Wenjie Zhang; Rachel Levy-Toledano; Boxiong Tang
Journal:  Int J Womens Health       Date:  2019-01-07
  4 in total

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