Literature DB >> 2270276

[The radiation modifying properties of carnosine].

S E Severin, A A Boldyrev, S L Stvolinskiĭ, M M Bordiukov, E N Goncharenko, L I Deev, I E Malinina, Iu B Kudriashov.   

Abstract

The influence of carnosine (beta-alanyl-l-histidine) on the survival rate of albino mice subjected to whole-body X-irradiation has been investigated. Carnosine (50-200 mg/kg/day) administered per os during a period of 20 days before irradiation (5.0 Gy) increased the survival rate by 45-65%, whereas the administration of carnosine within 30 days after irradiation (5.5 Gy) produced an insignificant protective effect and caused inhibition of the postirradiation histamine accumulation in the spleen.

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Year:  1990        PMID: 2270276

Source DB:  PubMed          Journal:  Radiobiologiia        ISSN: 0033-8192


  2 in total

Review 1.  Effects of beta-alanine on muscle carnosine and exercise performance: a review of the current literature.

Authors:  Julie Y Culbertson; Richard B Kreider; Mike Greenwood; Matthew Cooke
Journal:  Nutrients       Date:  2010-01-25       Impact factor: 5.717

2.  Carnosine inhibits carbonic anhydrase IX-mediated extracellular acidosis and suppresses growth of HeLa tumor xenografts.

Authors:  Zuzana Ditte; Peter Ditte; Martina Labudova; Veronika Simko; Filippo Iuliano; Miriam Zatovicova; Lucia Csaderova; Silvia Pastorekova; Jaromir Pastorek
Journal:  BMC Cancer       Date:  2014-05-22       Impact factor: 4.430

  2 in total

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