Hsiu-Nien Shen1, Chin-Li Lu, Chung-Yi Li. 1. Department of Intensive Care Medicine, Chi Mei Medical Center, National Cheng Kung University, Tainan, Taiwan. hsiunian@gmail.com
Abstract
OBJECTIVES: This study aimed to describe a 10-year epidemiological trend of patients with first-attack acute pancreatitis (AP) in Taiwan. METHODS: We analyzed 107,349 patients with first-attack AP from the Taiwan National Health Insurance Research Database between 2000 and 2009. Severe cases were defined according to a modified Atlanta classification. Incidence rates were standardized by direct method. RESULTS: During the study period, the median age of the patients increased from 49 to 55 years and the proportion of men decreased from 66.8% to 62.3%. The averaged annual incidence of first-attack AP was estimated at 36.9 per 100,000 persons and changed only slightly. Stratified analyses showed that the incidence increased in children (<15 years), elderly people (≥ 65 years), and patients with biliary cause, but decreased in young to middle-aged men (15-64 years). The prevalence of severe cases increased from 21.0% to 22.3%, which was mainly caused by an increase of acute organ dysfunction (from 9.7% to 14.1%). Despite that, hospital mortality decreased from 4.3% to 3.3% for all cases and from 18.5% to 13.3% for severe ones. CONCLUSIONS: The overall incidence of first-attack AP changed slightly in Taiwan, which differs from the increasing trend observed in most Western countries. Although more patients had severe attacks in recent years, hospital mortality declined.
OBJECTIVES: This study aimed to describe a 10-year epidemiological trend of patients with first-attack acute pancreatitis (AP) in Taiwan. METHODS: We analyzed 107,349 patients with first-attack AP from the Taiwan National Health Insurance Research Database between 2000 and 2009. Severe cases were defined according to a modified Atlanta classification. Incidence rates were standardized by direct method. RESULTS: During the study period, the median age of the patients increased from 49 to 55 years and the proportion of men decreased from 66.8% to 62.3%. The averaged annual incidence of first-attack AP was estimated at 36.9 per 100,000 persons and changed only slightly. Stratified analyses showed that the incidence increased in children (<15 years), elderly people (≥ 65 years), and patients with biliary cause, but decreased in young to middle-aged men (15-64 years). The prevalence of severe cases increased from 21.0% to 22.3%, which was mainly caused by an increase of acute organ dysfunction (from 9.7% to 14.1%). Despite that, hospital mortality decreased from 4.3% to 3.3% for all cases and from 18.5% to 13.3% for severe ones. CONCLUSIONS: The overall incidence of first-attack AP changed slightly in Taiwan, which differs from the increasing trend observed in most Western countries. Although more patients had severe attacks in recent years, hospital mortality declined.
Authors: Tommaso Giuliani; Giovanni Marchegiani; Mark D Girgis; Stefano Francesco Crinò; Venkataraman R Muthusamy; Laura Bernardoni; Antonio Pea; Marco Ramera; Salvatore Paiella; Luca Landoni; Armando Gabbrielli; Roberto Salvia; Timothy R Donahue; Claudio Bassi Journal: Surg Endosc Date: 2020-03-16 Impact factor: 4.584
Authors: Stephen A Firkins; Phil A Hart; Georgios I Papachristou; Luis F Lara; Zobeida Cruz-Monserrate; Alice Hinton; Darwin L Conwell; David P Bradley; Somashekar G Krishna Journal: Pancreas Date: 2021 May-Jun 01 Impact factor: 3.327