Literature DB >> 22697144

Modelling the epidemiological impact of scaling up HIV testing and antiretroviral treatment in China.

Lei Zhang1, Richard T Gray, David P Wilson.   

Abstract

BACKGROUND: The HIV epidemic in China has been increasing. In response, a 5-year action plan in China has prioritised the scale-up of HIV testing and treatment.
METHODS: We use a mathematical model to reproduce HIV epidemic trends in China and to forecast epidemic trends according to current conditions or increases in the rate of HIV testing or roll-out of antiretroviral therapy.
RESULTS: We show that the epidemic in China could be expected to experience a 2.5-fold expansion over the next 5 years such that ~1.8 million people will be infected with HIV in China by 2015. However, increasing testing and treatment rates can have substantial epidemiological benefits. For example, a four-fold increase in testing rates may avert more than 42000 HIV infections and 11000 deaths over the next 5 years. A 10-fold increase in the treatment rate could decrease the number of HIV-related deaths by 58% and the number of new infections by one-quarter by 2015.
CONCLUSIONS: Increasing HIV testing and treatment are important public health strategies for prevention.

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Year:  2012        PMID: 22697144     DOI: 10.1071/SH11104

Source DB:  PubMed          Journal:  Sex Health        ISSN: 1448-5028            Impact factor:   2.706


  15 in total

1.  Antiretroviral therapy and mental health among people living with HIV/AIDS in China.

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2.  Gynecologic pain related to occupational stress among female factory workers in Tianjin, China.

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4.  Barriers and Potential Improvements for Needle and Syringe Exchange Programs (NSPs) in China: A Qualitative Study from Perspectives of Both Health and Public Security Sectors.

Authors:  Fung Kuen Koo; Xi Chen; Eric P F Chow; Jun Jing; Jun Zheng; Junshi Zhao; Lei Zhang
Journal:  PLoS One       Date:  2015-06-26       Impact factor: 3.240

5.  HIV and hepatitis C virus test uptake at methadone clinics in Southern China: opportunities for expanding detection of bloodborne infections.

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Review 6.  HIV treatment as prevention: contradictory perspectives from dynamic mathematical models.

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Review 7.  Narrative review of models and success factors for scaling up public health interventions.

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8.  Modeling the impact on HIV incidence of combination prevention strategies among men who have sex with men in Beijing, China.

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Journal:  PLoS One       Date:  2014-03-13       Impact factor: 3.240

9.  HIV prevalence and high-risk sexual behaviours among MSM repeat and first-time testers in China: implications for HIV prevention.

Authors:  Xue Bai; Jie Xu; Jie Yang; Bo Yang; Maohe Yu; Yongjun Gao; Willa M Dong; Zunyou Wu
Journal:  J Int AIDS Soc       Date:  2014-07-02       Impact factor: 5.396

10.  Increased HIV Testing among Men Who Have Sex with Men from 2008 to 2012, Nanjing, China.

Authors:  Hongjing Yan; Jianjun Li; H Fisher Raymond; Xiping Huan; Wenhui Guan; Haiyang Hu; Haitao Yang; Willi McFarland; Chongyi Wei
Journal:  PLoS One       Date:  2016-04-25       Impact factor: 3.240

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