Literature DB >> 22696998

The safety of direct primary excision of low-grade chondral lesions based on radiological diagnosis alone.

Onur Berber1, Gorav Datta, Sanjeeve Sabharwal, Will Aston, Asif Saifuddin, Tim Briggs.   

Abstract

The safety of treating low-grade chondral tumours by primary surgery without a pre- operative diagnostic needle biopsy was assessed by looking at the concordance between radiological and histological diagnoses. A retrospective review of the departmental histopathology registry from 2005 to 2009 was performed to identify cases of intramedullary chondral lesions in the appendicular skeleton. Cases with a pre-operative needle biopsy and with recurrence were excluded. Correlation between radiological and histological diagnosis was investigated with kappa analysis. Of 53 patients, bone expansion was seen in 18.4%, endosteal scalloping in 42.9% and extraosseous extension in 143%. Concordance was 100% between the radiological and histological diagnoses (Kappa score = 1.0). If a radiological diagnosis of an enchondroma or low-grade chondrosarcoma is made, then direct surgical treatment without needle biopsy is safe. A biopsy should be considered if any atypical radiological features suggesting a high-grade chondrosarcoma exist. This increases the certainty of diagnosis and allows planning of surgical treatment.

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Year:  2012        PMID: 22696998

Source DB:  PubMed          Journal:  Acta Orthop Belg        ISSN: 0001-6462            Impact factor:   0.500


  8 in total

1.  The incidence and outcome of chondral tumours as incidental findings on investigation of shoulder pathology.

Authors:  S S Jassim; T Hilton; A Saifuddin; R Pollock
Journal:  Eur J Orthop Surg Traumatol       Date:  2019-08-17

2.  Is Needle Biopsy Clinically Useful in Preoperative Grading of Central Chondrosarcoma of the Pelvis and Long Bones?

Authors:  Pablo D Roitman; Germán L Farfalli; Miguel A Ayerza; D Luis Múscolo; Federico E Milano; Luis A Aponte-Tinao
Journal:  Clin Orthop Relat Res       Date:  2017-03       Impact factor: 4.176

3.  The importance of MRI review following the diagnosis of atypical cartilaginous tumour using image-guided needle biopsy.

Authors:  Asif Saifuddin; Ines Oliveira; Nehal Singla; Anesh Chavda; Michael Khoo; Paul O'Donnell
Journal:  Skeletal Radiol       Date:  2020-08-13       Impact factor: 2.199

Review 4.  Treatment strategies for central low-grade chondrosarcoma of long bones: a systematic review of the literature and meta-analysis.

Authors:  S S Shemesh; J D Acevedo-Nieves; J Pretell-Mazzini
Journal:  Musculoskelet Surg       Date:  2017-10-06

Review 5.  The role of MRI in image-guided needle biopsy of focal bone and soft tissue neoplasms.

Authors:  M M Y Khoo; A Saifuddin
Journal:  Skeletal Radiol       Date:  2013-05-04       Impact factor: 2.199

6.  Atypical Cartilaginous Tumors: Trends in Management.

Authors:  Matthew E Wells; Benjamin R Childs; Michael D Eckhoff; Rajiv Rajani; Benjamin K Potter; Elizabeth M Polfer
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2021-12-16

7.  Paediatric bone lesions: diagnostic accuracy of imaging correlation and CT-guided needle biopsy for differentiating benign from malignant lesions.

Authors:  Alessandro Vidoni; Ian Pressney; Asif Saifuddin
Journal:  Br J Radiol       Date:  2021-02-10       Impact factor: 3.039

8.  Radiologic follow-up of untreated enchondroma and atypical cartilaginous tumors in the long bones.

Authors:  Claudia Deckers; Bart H W Schreuder; Gerjon Hannink; Jacky W J de Rooy; Ingrid C M van der Geest
Journal:  J Surg Oncol       Date:  2016-10-03       Impact factor: 3.454

  8 in total

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