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Literature DB >> 22696425

Tunable biomolecular interaction and fluorescence quenching ability of graphene oxide: application to "turn-on" DNA sensing in biological media.

Bong Jin Hong¹, Zhi An, Owen C Compton, SonBinh T Nguyen.

Abstract

As a platform for "turn-on" DNA sensing, the level of oxidation of graphene oxide strongly affects its fluorescence quenching ability and binding interactions to single-stranded oligodeoxyribonucleotides (ssODNs), leading to a broad range of sensitivity. Fine-tuning the level of oxidation of graphene oxide yields a DNA-detection platform that is highly sensitive in serum and biological media.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2012 PMID： 22696425 PMCID： PMC3639316 DOI： 10.1002/smll.201200264

Source DB: PubMed Journal: Small ISSN： 1613-6810 Impact factor: 13.281

45 in total

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