| Literature DB >> 22695584 |
Jianjun Yang1, Tao Zhang, Hao Yang, Huabei Jiang.
Abstract
We describe a multispectral continuous-wave diffuse optical tomography (DOT) system that can be used for in vivo three-dimensional (3-D) imaging of seizure dynamics. Fast 3-D data acquisition is realized through a time multiplexing approach based on a parallel lighting configuration--our system can achieve 0.12 ms per source per wavelength and up to a 14 Hz sampling rate for a full set of data for 3-D DOT image reconstruction. The system is validated using both static and dynamic tissue-like phantoms. An initial in vivo experiment using a rat model of seizure is also demonstrated.Entities:
Mesh:
Substances:
Year: 2012 PMID: 22695584 PMCID: PMC3553592 DOI: 10.1364/AO.51.003461
Source DB: PubMed Journal: Appl Opt ISSN: 1559-128X Impact factor: 1.980