Literature DB >> 22693201

Giant melanoma of the scalp--discussion of a rare clinical presentation.

Cornelia S L Müller1, Louisa Hinterberger, Thomas Vogt, Claudia Pföhler.   

Abstract

An 84-year-old woman presented with ulcerated scalp lesions that had been mistreated as acute haemorrhagic eczema for several months. Examination showed confluent purple-blue-grey macules, papules and nodules covering a great portion of the parietofrontotemporal scalp with focal areas of ulceration. Dermatopathologic examination of two 5 mm punch biopsies confirmed an invasive malignant melanoma (Breslow thickness of 5 mm, clark level V). In addition, lymphangiosis melanomatosa, intravascular tumour growth and a diffuse infiltration of the subcutaneous tissue were seen. Possible treatment options (eg, surgery, irradiation, intralesional treatment) were discussed with the patient, but declined. It is important that clinicians are aware that melanomas may be large and biopsies are mandatory to avoid delayed diagnosis. Thus, a dermatologist has a pre-eminent position in diagnostic procedure.

Entities:  

Mesh:

Year:  2011        PMID: 22693201      PMCID: PMC3128370          DOI: 10.1136/bcr.12.2010.3643

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

Review 1.  Intralesional agents in the management of cutaneous malignancy: a review.

Authors:  Laurie M Good; Misha D Miller; Whitney A High
Journal:  J Am Acad Dermatol       Date:  2010-03-23       Impact factor: 11.527

2.  A giant primary cutaneous melanoma of the scalp--can it be that big?

Authors:  L Panajotovic; B Dordevic; M D Pavlovic
Journal:  J Eur Acad Dermatol Venereol       Date:  2007-11       Impact factor: 6.166

3.  Giant acral melanoma on the left thumb of a korean patient.

Authors:  Jae Hwan Kim; Se Yeong Jeong; Jae Bin Shin; Ki Woong Ro; Soo Hong Seo; Sang Wook Son; Il-Hwan Kim
Journal:  Ann Dermatol       Date:  2009-05-31       Impact factor: 1.444

4.  Acantholytic-like malignant melanoma: an unusual morphologic variant.

Authors:  Jose Aneiros-Fernández; Salvador Arias-Santiago; Jose Luis Diaz-Recuero; Francisco O'valle Ravassa; Francisco Nogales Fernández; Jose Aneiros Cachaza
Journal:  Am J Dermatopathol       Date:  2010-06       Impact factor: 1.533

Review 5.  [S-100 beta protein in serum, a tumor marker in malignant melanoma-- current state of knowledge and clinical experience].

Authors:  A Jäckel; M Deichmann; V Waldmann; M Bock; H Näher
Journal:  Hautarzt       Date:  1999-04       Impact factor: 0.751

6.  Giant melanoma: novel problem, same approach.

Authors:  Andre D Grisham
Journal:  South Med J       Date:  2010-11       Impact factor: 0.954

7.  Giant melanoma and depression.

Authors:  Javier del Boz; José Miguel García; Silvestre Martínez; Marina Gómez
Journal:  Am J Clin Dermatol       Date:  2009       Impact factor: 7.403

  7 in total

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