Literature DB >> 22693198

A large and massive abdominal venous thrombosis associated with the presence of a big axillary mass, lupus-like syndrome and antiphospholipid antibodies.

Elia Ascer1, Liv Goldstein Ascer, Magnus Gidlund.   

Abstract

This case report concerns a 40-year-old patient with an unspecific abdominal pain, diarrhoea, a big axillary mass and a previous pulmonary infection. After biopsy of the axillary mass the diagnosis of lymphoma was excluded based on the presence of cells expressing polyclonal antibodies. Abdominal CT scans and angionuclear magnetic resonance showed an extensive intestinal venous thrombosis. The patient also presented positive results for C and S proteins, lupic anticoagulant factor and antiphospholipid antibodies (anticardiolipin antibodies - IgM and IgG). Treatment started with administration of recombinant tissue plasminogen activator and heparin which decreased the degree of thrombosis. Antibiotics were also administrated to treat pulmonary and abdominal infections. After 25 days, he was discharged with no signs of infection, no abdominal pain and reduction of the thrombosis. He was medicated with warfarin, hydroxichloroquine and clopidogrel. Forty-five days after discharge, abdominal CT scan showed a significant regression of thrombosis.

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Year:  2011        PMID: 22693198      PMCID: PMC3128353          DOI: 10.1136/bcr.05.2011.4217

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  11 in total

Review 1.  Diagnosis and management of the antiphospholipid syndrome.

Authors:  Danielle Cohen; Stefan P Berger; Gerda M Steup-Beekman; Kitty W M Bloemenkamp; Ingeborg M Bajema
Journal:  BMJ       Date:  2010-05-14

Review 2.  Antiphospholipid syndrome dilemmas still to be solved: 2008 status.

Authors:  Yehuda Shoenfeld; Pier Luigi Meroni; Ricard Cervera
Journal:  Ann Rheum Dis       Date:  2008-04       Impact factor: 19.103

Review 3.  Antiphospholipid syndrome: frequency, main causes and risk factors of mortality.

Authors:  Gerard Espinosa; Ricard Cervera
Journal:  Nat Rev Rheumatol       Date:  2010-04-13       Impact factor: 20.543

Review 4.  [Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations].

Authors:  A Tincani; C Casu; S Cartella; T Ziglioli; R Cattaneo
Journal:  Reumatismo       Date:  2010 Jan-Mar

Review 5.  [Laboratory examinations in antiphospholipid syndrome].

Authors:  Masahiro Ieko; Sumiyoshi Naito; Mika Yoshida
Journal:  Rinsho Byori       Date:  2010-04

Review 6.  Pulmonary manifestations of the antiphospholipid antibody syndrome.

Authors:  H James Ford; Robert A S Roubey
Journal:  Clin Chest Med       Date:  2010-09       Impact factor: 2.878

Review 7.  Antiphospholipid syndrome (APS): where does it come from?

Authors:  Yaniv Sherer; Miri Blank; Yehuda Shoenfeld
Journal:  Best Pract Res Clin Rheumatol       Date:  2007-12       Impact factor: 4.098

Review 8.  Biomarkers and venous thromboembolism.

Authors:  Ingrid Pabinger; Cihan Ay
Journal:  Arterioscler Thromb Vasc Biol       Date:  2009-03       Impact factor: 8.311

Review 9.  Evidence-based indications for thrombophilia screening.

Authors:  E Lindhoff-Last; B Luxembourg
Journal:  Vasa       Date:  2008-02       Impact factor: 1.961

10.  The immunologic characterization of 40 extranodal lymphoid infiltrates: usefulness in distinguishing between benign pseudolymphoma and malignant lymphoma.

Authors:  D M Knowles; J P Halper; F A Jakobiec
Journal:  Cancer       Date:  1982-06-01       Impact factor: 6.860

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