Literature DB >> 22692876

Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis.

Bart J Crielaard1, Cristianne J F Rijcken, Lingdong Quan, Steffen van der Wal, Isil Altintas, Martin van der Pot, John A W Kruijtzer, Rob M J Liskamp, Raymond M Schiffelers, Cornelus F van Nostrum, Wim E Hennink, Dong Wang, Twan Lammers, Gert Storm.   

Abstract

Polymerizable and hydrolytically cleavable dexamethasone (DEX, red dot in picture) derivatives were covalently entrapped in core-cross-linked polymeric micelles that were prepared from a thermosensitive block copolymer (yellow and gray building block). By varying the oxidation degree of the thioether in the drug linker, the release rate of DEX could be controlled. The DEX-loaded micelles were used for efficient treatment of inflammatory arthritis in two animal models.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22692876      PMCID： PMC3499037          DOI： 10.1002/anie.201202713

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  30 in total

1.  Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change.

Authors:  Younsoo Bae; Shigeto Fukushima; Atsushi Harada; Kazunori Kataoka
Journal:  Angew Chem Int Ed Engl       Date:  2003-10-06       Impact factor: 15.336

Review 2.  Recent advances with liposomes as pharmaceutical carriers.

Authors:  Vladimir P Torchilin
Journal:  Nat Rev Drug Discov       Date:  2005-02       Impact factor: 84.694

3.  Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis.

Authors:  W van Eden; J E Thole; R van der Zee; A Noordzij; J D van Embden; E J Hensen; I R Cohen
Journal:  Nature       Date:  1988-01-14       Impact factor: 49.962

4.  Degradation kinetics of methacrylated dextrans in aqueous solution.

Authors:  W N van Dijk-Wolthuis; M J van Steenbergen; W J Underberg; W E Hennink
Journal:  J Pharm Sci       Date:  1997-04       Impact factor: 3.534

5.  Novel fast degradable thermosensitive polymeric micelles based on PEG-block-poly(N-(2-hydroxyethyl)methacrylamide-oligolactates).

Authors:  Cristianne J F Rijcken; Theo F J Veldhuis; Aissa Ramzi; Johannes D Meeldijk; Cornelus F van Nostrum; Wim E Hennink
Journal:  Biomacromolecules       Date:  2005 Jul-Aug       Impact factor: 6.988

6.  Permeability of human synovial membrane to plasma proteins. Relationship to molecular size and inflammation.

Authors:  I Kushner; J A Somerville
Journal:  Arthritis Rheum       Date:  1971 Sep-Oct

7.  Block copolymer micelles for drug delivery: design, characterization and biological significance.

Authors:  K Kataoka; A Harada; Y Nagasaki
Journal:  Adv Drug Deliv Rev       Date:  2001-03-23       Impact factor: 15.470

8.  Liposomes as carriers for colchicine-derived prodrugs: vascular disrupting nanomedicines with tailorable drug release kinetics.

Authors:  Bart J Crielaard; Steffen van der Wal; Huong Thu Le; Aloïs T L Bode; Twan Lammers; Wim E Hennink; Raymond M Schiffelers; Marcel H A M Fens; Gert Storm
Journal:  Eur J Pharm Sci       Date:  2011-09-01       Impact factor: 4.384

9.  The arthrotropism of macromolecules in adjuvant-induced arthritis rat model: a preliminary study.

Authors:  Dong Wang; Scott C Miller; Monika Sima; Dennis Parker; Henry Buswell; K Craig Goodrich; Pavla Kopecková; Jindrich Kopecek
Journal:  Pharm Res       Date:  2004-10       Impact factor: 4.200

10.  The effect of the linker on the hydrolysis rate of drug-linked ester bonds.

Authors:  Ronald G Schoenmakers; Petra van de Wetering; Donald L Elbert; Jeffrey A Hubbell
Journal:  J Control Release       Date:  2004-03-05       Impact factor: 9.776
View more
  26 in total

Review 1.  Targeting the extracellular matrix for delivery of bioactive molecules to sites of arthritis.

Authors:  Christopher Schultz
Journal:  Br J Pharmacol       Date:  2018-11-22       Impact factor: 8.739

Review 2.  Particle-based technologies for osteoarthritis detection and therapy.

Authors:  Taylor E Kavanaugh; Thomas A Werfel; Hongsik Cho; Karen A Hasty; Craig L Duvall
Journal:  Drug Deliv Transl Res       Date:  2016-04       Impact factor: 4.617

3.  Multi-arm Avidin nano-construct for intra-cartilage delivery of small molecule drugs.

Authors:  Tengfei He; Chenzhen Zhang; Armin Vedadghavami; Shikhar Mehta; Heather A Clark; Ryan M Porter; Ambika G Bajpayee
Journal:  J Control Release       Date:  2019-12-13       Impact factor: 9.776

4.  Redox-responsive, core-cross-linked micelles capable of on-demand, concurrent drug release and structure disassembly.

Authors:  Hua Wang; Li Tang; Chunlai Tu; Ziyuan Song; Qian Yin; Lichen Yin; Zhonghai Zhang; Jianjun Cheng
Journal:  Biomacromolecules       Date:  2013-09-23       Impact factor: 6.988

5.  Imaging the delivery of drug-loaded, iron-stabilized micelles.

Authors:  Suzanne J Bakewell; Adam Carie; Tara L Costich; Jyothi Sethuraman; J Edward Semple; Bradford Sullivan; Gary V Martinez; William Dominguez-Viqueira; Kevin N Sill
Journal:  Nanomedicine       Date:  2017-01-20       Impact factor: 5.307

Review 6.  Reversibly crosslinked nanocarriers for on-demand drug delivery in cancer treatment.

Authors:  Yu Shao; Wenzhe Huang; Changying Shi; Sean T Atkinson; Juntao Luo
Journal:  Ther Deliv       Date:  2012-12

Review 7.  Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems.

Authors:  Mahdi Karimi; Amir Ghasemi; Parham Sahandi Zangabad; Reza Rahighi; S Masoud Moosavi Basri; H Mirshekari; M Amiri; Z Shafaei Pishabad; A Aslani; M Bozorgomid; D Ghosh; A Beyzavi; A Vaseghi; A R Aref; L Haghani; S Bahrami; Michael R Hamblin
Journal:  Chem Soc Rev       Date:  2016-03-07       Impact factor: 54.564

8.  Core-Crosslinked Polymeric Micelles: Principles, Preparation, Biomedical Applications and Clinical Translation.

Authors:  Marina Talelli; Matthias Barz; Cristianne J Rijcken; Fabian Kiessling; Wim E Hennink; Twan Lammers
Journal:  Nano Today       Date:  2015-02-01       Impact factor: 20.722

9.  Fluorophore labeling of core-crosslinked polymeric micelles for multimodal in vivo and ex vivo optical imaging.

Authors:  Yang Shi; Sijumon Kunjachan; Zhuojun Wu; Felix Gremse; Diana Moeckel; Marc van Zandvoort; Fabian Kiessling; Gert Storm; Cornelus F van Nostrum; Wim E Hennink; Twan Lammers
Journal:  Nanomedicine (Lond)       Date:  2015       Impact factor: 5.307

10.  Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes.

Authors:  Lingdong Quan; Yijia Zhang; Bart J Crielaard; Anand Dusad; Subodh M Lele; Cristianne J F Rijcken; Josbert M Metselaar; Hana Kostková; Tomáš Etrych; Karel Ulbrich; Fabian Kiessling; Ted R Mikuls; Wim E Hennink; Gert Storm; Twan Lammers; Dong Wang
Journal:  ACS Nano       Date:  2013-12-27       Impact factor: 15.881
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.