Literature DB >> 22692558

An activity-based fluorogenic probe for sensitive and selective monoamine oxidase-B detection.

Shaobo Long1, Lin Chen, Yumi Xiang, Minggui Song, Yuguo Zheng, Qing Zhu.   

Abstract

We report the design and synthesis of a new class of fluorogenic probes based on monoamine oxidase-triggered oxidative C-O bond cleavage. The selectivity of probe P1 towards MAO-B was 22-fold higher than that towards MAO-A.

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Year:  2012        PMID： 22692558     DOI： 10.1039/c2cc33089j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Evaluation of Enzyme Substrate Radiotracers as PET/MRS Hybrid Imaging Agents.

Authors:  Allen F Brooks; Lindsey R Drake; Xia Shao; Austin Zhao; Peter J H Scott; Michael R Kilbourn
Journal:  ACS Med Chem Lett       Date:  2018-10-03       Impact factor: 4.345

2.  In Vivo Metabolic Trapping Radiotracers for Imaging Monoamine Oxidase-A and -B Enzymatic Activity.

Authors:  Allen F Brooks; Xia Shao; Carole A Quesada; Phillip Sherman; Peter J H Scott; Michael R Kilbourn
Journal:  ACS Chem Neurosci       Date:  2015-10-01       Impact factor: 4.418

Review 3.  Optical substrates for drug-metabolizing enzymes: Recent advances and future perspectives.

Authors:  Qiang Jin; JingJing Wu; Yue Wu; Hongxin Li; Moshe Finel; Dandan Wang; Guangbo Ge
Journal:  Acta Pharm Sin B       Date:  2022-01-21       Impact factor: 14.903

4.  Multiexcitation Fluorogenic Labeling of Surface, Intracellular, and Total Protein Pools in Living Cells.

Authors:  Matharishwan Naganbabu; Lydia A Perkins; Yi Wang; Jeffery Kurish; Brigitte F Schmidt; Marcel P Bruchez
Journal:  Bioconjug Chem       Date:  2016-05-19       Impact factor: 4.774

5.  Red emission fluorescent probes for visualization of monoamine oxidase in living cells.

Authors:  Ling-Ling Li; Kun Li; Yan-Hong Liu; Hao-Ran Xu; Xiao-Qi Yu
Journal:  Sci Rep       Date:  2016-08-08       Impact factor: 4.379

6.  Optical molecular imaging of lysyl oxidase activity - detection of active fibrogenesis in human lung tissue.

Authors:  Tashfeen Aslam; Amy Miele; Sunay V Chankeshwara; Alicia Megia-Fernandez; Chesney Michels; Ahsan R Akram; Neil McDonald; Nik Hirani; Chris Haslett; Mark Bradley; Kevin Dhaliwal
Journal:  Chem Sci       Date:  2015-06-08       Impact factor: 9.825
  6 in total

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