Literature DB >> 22692458

A highly selective G-quadruplex-based luminescent switch-on probe for the detection of gene deletion.

Hong-Zhang He1, Daniel Shiu-Hin Chan, Chung-Hang Leung, Dik-Lung Ma.   

Abstract

A G-quadruplex-based switch-on luminescence assay has been developed for the detection of gene deletion using a cyclometallated iridium(III) complex as a G-quadruplex-selective probe. Upon hybridization with the target DNA, the two split G-quadruplex-forming sequences assemble into a split G-quadruplex, which greatly enhances the luminescence emission of the iridium(III) probe. The assay is simple and highly selective.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22692458     DOI： 10.1039/c2cc32253f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

1.  Fluorescent C-NanoDots for rapid detection of BRCA1, CFTR and MRP3 gene mutations.

Authors:  Tania García-Mendiola; Cristina Garcia Elosegui; Iria Bravo; Félix Pariente; Alejandra Jacobo-Martin; Cristina Navio; Isabel Rodriguez; Reinhold Wannemacher; Encarnación Lorenzo
Journal:  Mikrochim Acta       Date:  2019-04-23       Impact factor: 5.833

2.  Cyclometalated rhodium and iridium complexes with imidazole containing Schiff bases: Synthesis, structure and cellular imaging.

Authors:  Soumik Mandal; Dipak K Poria; Dipravath K Seth; Partho Sarothi Ray; Parna Gupta
Journal:  Polyhedron       Date:  2014-02-10       Impact factor: 3.052

Review 3.  G-quadruplexes for luminescent sensing and logic gates.

Authors:  Hong-Zhang He; Daniel Shiu-Hin Chan; Chung-Hang Leung; Dik-Lung Ma
Journal:  Nucleic Acids Res       Date:  2013-02-23       Impact factor: 16.971

4.  The presence of a single-nucleotide mismatch in linker increases the fluorescence of guanine-enhanced DNA-templated Ag nanoclusters and their application for highly sensitive detection of cyanide.

Authors:  Jun Peng; Jian Ling; Qiu-Lin Wen; Yu Li; Qiu-E Cao; Zhang-Jie Huang; Zhong-Tao Ding
Journal:  RSC Adv       Date:  2018-12-12       Impact factor: 4.036

5.  A label-free luminescent switch-on assay for ATP using a G-quadruplex-selective iridium(III) complex.

Authors:  Ka-Ho Leung; Lihua Lu; Modi Wang; Tsun-Yin Mak; Daniel Shiu-Hin Chan; Fung-Kit Tang; Chung-Hang Leung; Hiu-Yee Kwan; Zhiling Yu; Dik-Lung Ma
Journal:  PLoS One       Date:  2013-10-25       Impact factor: 3.240

6.  A colorimetric and luminescent dual-modal assay for Cu(II) ion detection using an iridium(III) complex.

Authors:  Dik-Lung Ma; Hong-Zhang He; Daniel Shiu-Hin Chan; Chun-Yuen Wong; Chung-Hang Leung
Journal:  PLoS One       Date:  2014-06-13       Impact factor: 3.240

7.  A colorimetric chemosensor for Cu²⁺ ion detection based on an iridium(III) complex.

Authors:  Modi Wang; Ka-Ho Leung; Sheng Lin; Daniel Shiu-Hin Chan; Daniel W J Kwong; Chung-Hang Leung; Dik-Lung Ma
Journal:  Sci Rep       Date:  2014-10-28       Impact factor: 4.379

8.  Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence.

Authors:  Bo Zhou; Yanyan Geng; Changdong Liu; Haitao Miao; Yaguang Ren; Naining Xu; Xiao Shi; Yingying You; Tunglun Lee; Guang Zhu
Journal:  Sci Rep       Date:  2018-02-05       Impact factor: 4.379

9.  Enzyme-mediated single-nucleotide variation detection at room temperature with high discrimination factor.

Authors:  Tongbo Wu; Xianjin Xiao; Zhe Zhang; Meiping Zhao
Journal:  Chem Sci       Date:  2014-11-07       Impact factor: 9.825

Review 10.  Nucleic acid detection using G-quadruplex amplification methodologies.

Authors:  Benjamin T Roembke; Shizuka Nakayama; Herman O Sintim
Journal:  Methods       Date:  2013-10-14       Impact factor: 3.608
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.